» Articles » PMID: 38406073

Giant Cell Tumor of the Frontal Bone: A Rare Case Report and Review of Literature

Overview
Journal Cureus
Date 2024 Feb 26
PMID 38406073
Authors
Affiliations
Soon will be listed here.
Abstract

Giant cell tumors (GCTs), typically benign, predominantly manifest in individuals aged 20-40, with the most common locations being the metaphysis or epiphysis of the femur or tibia. Infrequently, they may occur in the skull. Despite their benign nature, these tumors can exhibit aggressive behavior and have the potential to metastasize. In the case at hand, a 20-year-old female presented to the hospital with a progressively enlarging right frontal swelling over the preceding months. The patient reported intermittent headaches, alleviated by analgesics, and exhibited a normal neurological examination along with a Glasgow Coma Scale (GCS) score of 15 out of 15. Imaging revealed an expansive soft tissue mass in the right frontal bone involving both inner and outer tables. Surgical intervention was pursued through a right frontal incision followed by tumor excision. Histopathological examination of the specimen confirmed the presence of a GCT. The limited existing literature on this topic highlights the need for further research and insights into effective strategies. This case contributes to addressing this gap in knowledge, offering valuable information to enhance our understanding of the challenges associated with similar rare cases and improve patient outcomes.

References
1.
Wang H, Wan N, Hu Y . Giant cell tumour of bone: a new evaluating system is necessary. Int Orthop. 2012; 36(12):2521-7. PMC: 3508056. DOI: 10.1007/s00264-012-1664-9. View

2.
Jadidi S, DAbarno A, Barkley J, Abusuwwa R . Giant Cell Tumor of the Frontal Bone: A Case Report and Literature Review. Cureus. 2018; 10(9):e3353. PMC: 6255713. DOI: 10.7759/cureus.3353. View

3.
Mavrogenis A, Igoumenou V, Megaloikonomos P, Panagopoulos G, Papagelopoulos P, Soucacos P . Giant cell tumor of bone revisited. SICOT J. 2017; 3:54. PMC: 5598212. DOI: 10.1051/sicotj/2017041. View

4.
Kattner K, Stroink A, Gupta K, Fukushima T, Li C . Giant cell tumor of the sphenoid bone. Skull Base Surg. 2006; 8(2):93-7. PMC: 1656693. DOI: 10.1055/s-2008-1058582. View

5.
Osaka S, Toriyama S . Surgical treatment of giant cell tumors of the pelvis. Clin Orthop Relat Res. 1987; (222):123-31. View