Gender Medicine and Pharmacology

Overview

Journal Biomedicines

Specialty Biomedical Engineering

Date 2024 Feb 24

PMID 38397867

Authors

Sarah Allegra

Francesco Chiara

Silvia De Francia

Affiliations

Soon will be listed here.

Abstract

Gender-specific medicine consists of a transversal methodological approach that aims to study the influence of sex and gender on diseases [...].

Citing Articles

Ceruloplasmin administration in the preclinical mouse model of aceruloplasminemia reveals a sex-related variation in biodistribution.

Belloli S, Monterisi C, Rainone P, Coliva A, Zanardi A, Conti A Commun Biol. 2025; 8(1):264.

PMID: 39972187 PMC: 11839944. DOI: 10.1038/s42003-025-07714-8.

Gender-Specific Survival of Nasopharyngeal Carcinoma in Endemic and Non-Endemic Areas Based on the US SEER Database and a Chinese Single-Institutional Registry.

Guo L, Dai Y, Yu Y, Wu S Clin Epidemiol. 2024; 16:769-782.

PMID: 39539417 PMC: 11559420. DOI: 10.2147/CLEP.S490023.

References

Gupta S, Atkinson L, Tu T, Longstreth J . Age and gender related changes in stereoselective pharmacokinetics and pharmacodynamics of verapamil and norverapamil. Br J Clin Pharmacol. 1995; 40(4):325-31. PMC: 1365151. DOI: 10.1111/j.1365-2125.1995.tb04554.x. View

Gandhi M, Aweeka F, Greenblatt R, Blaschke T . Sex differences in pharmacokinetics and pharmacodynamics. Annu Rev Pharmacol Toxicol. 2004; 44:499-523. DOI: 10.1146/annurev.pharmtox.44.101802.121453. View

Dawkins K, Potter W . Gender differences in pharmacokinetics and pharmacodynamics of psychotropics: focus on women. Psychopharmacol Bull. 1991; 27(4):417-26. View

Barnas C, Slimko J, Jones M, Schwartz J . Gender-specific effects on verapamil pharmacokinetics and pharmacodynamics in humans. J Clin Pharmacol. 2000; 40(3):219-30. DOI: 10.1177/00912700022008883. View

Escorial M, Muriel J, Margarit C, Agullo L, Morales D, Peiro Peiro A . Sex-Differences in Pain and Opioid Use Disorder Management: A Cross-Sectional Real-World Study. Biomedicines. 2022; 10(9). PMC: 9496267. DOI: 10.3390/biomedicines10092302. View

Wonisch W, Falk A, Sundl I, Winklhofer-Roob B, Lindschinger M . Oxidative stress increases continuously with BMI and age with unfavourable profiles in males. Aging Male. 2012; 15(3):159-65. DOI: 10.3109/13685538.2012.669436. View

Figueiredo M, Gagliano-Juca T, Basaria S . Male Reproduction and Aging. Endocrinol Metab Clin North Am. 2023; 52(2):211-228. DOI: 10.1016/j.ecl.2022.12.002. View

Jiang X, Samant S, Lesko L, Schmidt S . Clinical pharmacokinetics and pharmacodynamics of clopidogrel. Clin Pharmacokinet. 2015; 54(2):147-66. PMC: 5677184. DOI: 10.1007/s40262-014-0230-6. View

Frost C, Song Y, Shenker A, Wang J, Barrett Y, Schuster A . Effects of age and sex on the single-dose pharmacokinetics and pharmacodynamics of apixaban. Clin Pharmacokinet. 2015; 54(6):651-62. PMC: 4449375. DOI: 10.1007/s40262-014-0228-0. View

10.

Ueno K, Sato H . Sex-related differences in pharmacokinetics and pharmacodynamics of anti-hypertensive drugs. Hypertens Res. 2011; 35(3):245-50. DOI: 10.1038/hr.2011.189. View

11.

Dawkins K, Rudorfer M, Potter W . Comments on gender differences in pharmacokinetics and pharmacodynamics. Am J Psychiatry. 1993; 150(4):678-9. DOI: 10.1176/ajp.150.4.aj1504678. View

12.

Jordens M, Wittig L, Loberg C, Heinrichs L, Keitel V, Schulze-Hagen M . Bone Mineral Density Is a Predictor of Mortality in Female Patients with Cholangiocellular Carcinoma Undergoing Palliative Treatment. Biomedicines. 2022; 10(7). PMC: 9313370. DOI: 10.3390/biomedicines10071660. View

13.

Yoon S, Jeong S, Jung E, Kim K, Jeon I, Lee Y . Effect of CYP3A4 metabolism on sex differences in the pharmacokinetics and pharmacodynamics of zolpidem. Sci Rep. 2021; 11(1):19150. PMC: 8476623. DOI: 10.1038/s41598-021-98689-z. View

14.

Sirufo M, Pietro F, Ginaldi L, De Martinis M . Sex, Allergic Diseases and Omalizumab. Biomedicines. 2022; 10(2). PMC: 8869622. DOI: 10.3390/biomedicines10020328. View

15.

de Vries F, Bruin M, Lobatto D, Dekkers O, Schoones J, van Furth W . Opioids and Their Endocrine Effects: A Systematic Review and Meta-analysis. J Clin Endocrinol Metab. 2019; 105(3). PMC: 7054712. DOI: 10.1210/clinem/dgz022. View

16.

Vachharajani N, Raymond R, Shyu W, Stouffer B, Boulton D . The effects of age and gender on the pharmacokinetics and pharmacodynamics in healthy subjects of the plasminogen activator, lanoteplase. Br J Clin Pharmacol. 2011; 72(5):775-86. PMC: 3243012. DOI: 10.1111/j.1365-2125.2011.04003.x. View

17.

Regitz-Zagrosek V . [Sex and gender differences in pharmacotherapy]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2014; 57(9):1067-73. DOI: 10.1007/s00103-014-2012-6. View

18.

Barrachina J, Margarit C, Muriel J, Lopez-Gil V, Lopez-Gil S, Ballester P . Sex Differences in Oxycodone/Naloxone vs. Tapentadol in Chronic Non-Cancer Pain: An Observational Real-World Study. Biomedicines. 2022; 10(10). PMC: 9598624. DOI: 10.3390/biomedicines10102468. View

19.

Bies R, Bigos K, Pollock B . Gender differences in the pharmacokinetics and pharmacodynamics of antidepressants. J Gend Specif Med. 2003; 6(3):12-20. View

20.

Wu F, Tajar A, Pye S, Silman A, Finn J, ONeill T . Hypothalamic-pituitary-testicular axis disruptions in older men are differentially linked to age and modifiable risk factors: the European Male Aging Study. J Clin Endocrinol Metab. 2008; 93(7):2737-45. DOI: 10.1210/jc.2007-1972. View