CSMed Wound Dressing for Prophylaxis and Management of Radiation Dermatitis in Breast and Head-neck Cancer Patients: a Single Hospital Prospective Clinical Trial

Overview

Journal J Cancer Res Clin Oncol

Specialty Oncology

Date 2024 Feb 23

PMID 38393390

Authors

Yueh-Chun Lee

Hsien-Chun Tseng

Huei-Fang Yang

Yi-Hung Lee

Ya-Fang Ko

Shin-Tsung Chang

Hsin-Lin Chen

Bo-Jiun Chang

Ying-Hsiang Chou

Affiliations

Soon will be listed here.

Abstract

Purpose: CSMed wound dressing, a dressing with various herb extracts, was tested for its therapeutic effect in radiation dermatitis of breast and head-and-neck cancer patients.

Methods: This study included 20 breast cancer patients and 10 head-and-neck cancer patients. Half of the irradiated area was covered with CSMed and the other half was under routine treatment. The severity of radiation dermatitis was evaluated with radiation therapy oncology group (RTOG) grade throughout the treatment and the follow-up period. The RTOG grade between the dressed and undressed area were compared to illustrate the therapeutic effect of CSMed dressing.

Results: The results showed that CSMed dressed area had significant lower RTOG score at 3-7 weeks and final record during the treatment, and 1-3 weeks during follow-up than undressed area.

Conclusions: This indicated that CSMed can delay the onset, reduce the severity, and enhance healing of radiation dermatitis. CSMed can be used for prophylaxis and management of radiation dermatitis.

Citing Articles

Radiation-induced skin reactions: oxidative damage mechanism and antioxidant protection.

Liu C, Wei J, Wang X, Zhao Q, Lv J, Tan Z Front Cell Dev Biol. 2024; 12:1480571.

PMID: 39450273 PMC: 11500330. DOI: 10.3389/fcell.2024.1480571.

Evidence-based summary of the prevention and management of radiation dermatitis in patients with breast cancer.

Chen X, Li X, Wang Z, Zheng R, Zhang F, Zhao J Asia Pac J Oncol Nurs. 2024; 11(9):100556.

PMID: 39220149 PMC: 11362797. DOI: 10.1016/j.apjon.2024.100556.

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