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A National Audit of the Care of Patients with Acute Kidney Injury in England and Wales in 2019 and the Association with Patient Outcomes

Overview
Journal Clin Med (Lond)
Specialty General Medicine
Date 2024 Feb 22
PMID 38387536
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Abstract

Background: Acute kidney injury (AKI) is a common complication of hospitalisations. This national audit assessed the care received by patients with AKI in hospital Trusts in England and Wales.

Methods: Twenty four hospital Trusts across England and Wales took part. Patients with AKI stage2/3 were identified using the UK Renal Registry AKI master patient index. Data was returned through a secure portal with linkage to hospital episode statistic mortality and hospitalisation data. Completion rates of AKI care standards and regional variations in care were established.

Results: 989 AKI episodes were included in the analyses. In-hospital 30-day mortality was 31-33.1% (AKI 2/3). Standard AKI interventions were completed in >80% of episodes. Significant inter-hospital variation remained in attainment of AKI care standards after adjustment for age and sex. Recording of urinalysis (41.9%) and timely imaging (37.2%) were low. Information on discharge summaries relating to medication changes/re-commencement and follow-up blood tests associated with reduced mortality. No quality indicators relating to clinical management associated with mortality. Better communication on discharge summaries associated with reduced mortality.

Conclusions: Outcomes for patients with AKI in hospital remain poor. Regional variation in care exists. Work is needed to assess whether improving and standardising care improves patient outcomes.

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Saravanan P Clin Med (Lond). 2024; 24(2):100201.

PMID: 38729741 PMC: 11091438. DOI: 10.1016/j.clinme.2024.100201.

References
1.
Holmes J, Rainer T, Geen J, Roberts G, May K, Wilson N . Acute Kidney Injury in the Era of the AKI E-Alert. Clin J Am Soc Nephrol. 2016; 11(12):2123-2131. PMC: 5142071. DOI: 10.2215/CJN.05170516. View

2.
Savino M, Plumb L, Casula A, Evans K, Wong E, Kolhe N . Acute kidney injury identification for pharmacoepidemiologic studies: Use of laboratory electronic acute kidney injury alerts versus electronic health records in Hospital Episode Statistics. Pharmacoepidemiol Drug Saf. 2021; 30(12):1687-1695. DOI: 10.1002/pds.5347. View

3.
Lameire N, Bagga A, Cruz D, De Maeseneer J, Endre Z, Kellum J . Acute kidney injury: an increasing global concern. Lancet. 2013; 382(9887):170-9. DOI: 10.1016/S0140-6736(13)60647-9. View

4.
Selby N, Casula A, Lamming L, Stoves J, Samarasinghe Y, Lewington A . An Organizational-Level Program of Intervention for AKI: A Pragmatic Stepped Wedge Cluster Randomized Trial. J Am Soc Nephrol. 2019; 30(3):505-515. PMC: 6405151. DOI: 10.1681/ASN.2018090886. View

5.
Peracha J, Pitcher D, Santhakumaran S, Steenkamp R, Fotheringham J, Day J . Centre variation in mortality following post-hospitalization acute kidney injury: analysis of a large national cohort. Nephrol Dial Transplant. 2021; 37(11):2201-2213. DOI: 10.1093/ndt/gfab348. View