Pharmacological Semen Collection in Domestic and Wild Canids and Felids: Literature Review

Overview

Journal Anim Reprod

Date 2024 Feb 21

PMID 38380384

Authors

Jeandson da Silva Carneiro

Tathiana Ferguson Motheo

Affiliations

Soon will be listed here.

Abstract

Semen collection methods vary greatly and rely on the practitioner's expertise, available materials, and the specific behavioral traits of the male animals involved. When it comes to domestic cats, wild felids, and canids, semen collection is particularly challenging. Thus, given the difficulty of semen collection in these species, pharmacological semen collection (PSC) stands out since it is a quick and straightforward method that does not require specific equipment. The PSC consists of administering α2-adrenergic receptor agonist drugs, mainly medetomidine, and dexmedetomidine, aiming semen release into the urethra with posterior urethral catheterization and sperm recovery. This technique was primarily described in domestic cats and wild felids, and despite the decreased seminal volume, the retrieved semen is highly concentrated and presents good quality. However, further studies are required to optimize semen collection in domestic dogs and wild canids. Therefore, the purpose of this review is to provide a comprehensive overview of the research developed on pharmacological semen collection (PSC) in the past few decades. The objective is to equip professionals with the essential knowledge required for the efficient application of this technique in both domestic and wild canids and felids and to make a valuable contribution to conservation efforts and the preservation of biodiversity, aligning with the principles of One Conservation.

References

Kheirkhah M, Mollapour Sisakht M, Mohammadsadegh M, Moslemi H . Sperm evaluation of Jungle Cat (Felis chaus) obtained by urethral catheterization (CT) after medetomidine administration. Theriogenology. 2017; 91:17-20. DOI: 10.1016/j.theriogenology.2016.12.034. View

Prochowska S, Nizanski W, Partyka A . Comparative analysis of in vitro characteristics of fresh and frozen-thawed urethral and epididymal spermatozoa from cats (Felis domesticus). Theriogenology. 2016; 86(8):2063-72. DOI: 10.1016/j.theriogenology.2016.07.002. View

Hidalgo M, Almeida A, Dos Santos Silva L, Greghi J, Silva V, Sambatti N . Comparison of two pharmacological semen collection times with α2-adrenergic agonist in domestic cats. Reprod Domest Anim. 2023; 58(9):1207-1213. DOI: 10.1111/rda.14420. View

Pizzutto C, Colbachini H, Jorge-Neto P . One Conservation: the integrated view of biodiversity conservation. Anim Reprod. 2021; 18(2):e20210024. PMC: 8190570. DOI: 10.1590/1984-3143-AR2021-0024. View

Prochowska S, Nizanski W . In vitro fertilizing potential of urethral and epididymal spermatozoa collected from domestic cats (Felis catus). Pol J Vet Sci. 2017; 20(1):19-24. DOI: 10.1515/pjvs-2017-0003. View

Jeong D, Kim J, Na K . Characterization and cryopreservation of Amur leopard cats (Prionailurus bengalensis euptilurus) semen collected by urethral catheterization. Theriogenology. 2018; 119:91-95. DOI: 10.1016/j.theriogenology.2018.06.004. View

Swanson W, Bateman H, Vansandt L . Urethral catheterization and sperm vitrification for simplified semen banking in felids. Reprod Domest Anim. 2016; 52 Suppl 2:255-260. DOI: 10.1111/rda.12863. View

Zambelli D, Prati F, Cunto M, Iacono E, Merlo B . Quality and in vitro fertilizing ability of cryopreserved cat spermatozoa obtained by urethral catheterization after medetomidine administration. Theriogenology. 2007; 69(4):485-90. DOI: 10.1016/j.theriogenology.2007.10.019. View

Virtanen R, Savola J, Saano V, Nyman L . Characterization of the selectivity, specificity and potency of medetomidine as an alpha 2-adrenoceptor agonist. Eur J Pharmacol. 1988; 150(1-2):9-14. DOI: 10.1016/0014-2999(88)90744-3. View

10.

Romagnoli N, Lambertini C, Zambelli D, Cunto M, Ballotta G, Barbarossa A . Plasma Concentration Rise after the Intramuscular Administration of High Dose Medetomidine (0.13 mg/kg) for Semen Collection in Cats. Vet Sci. 2020; 7(1). PMC: 7157624. DOI: 10.3390/vetsci7010017. View

11.

Cunto M, Kuster D, Bini C, Cartolano C, Pietra M, Zambelli D . Influence of Different Protocols of Urethral Catheterization after Pharmacological Induction (Ur.Ca.P.I.) on Semen Quality in the Domestic Cat. Reprod Domest Anim. 2015; 50(6):999-1002. DOI: 10.1111/rda.12626. View

12.

Filliers M, Rijsselaere T, Bossaert P, Zambelli D, Anastasi P, Hoogewijs M . In vitro evaluation of fresh sperm quality in tomcats: a comparison of two collection techniques. Theriogenology. 2010; 74(1):31-9. DOI: 10.1016/j.theriogenology.2009.12.016. View

13.

Prochowska S, Nizanski W, Ochota M, Partyka A . Characteristics of urethral and epididymal semen collected from domestic cats--A retrospective study of 214 cases. Theriogenology. 2015; 84(9):1565-71. DOI: 10.1016/j.theriogenology.2015.08.005. View

14.

Jorge-Neto P, Luczinski T, de Araujo G, Requena L, de Jesus R, Souza L . Cryopreservation of jaguar () sperm cells using different cryoprotectants and different thawing temperatures. Anim Reprod. 2023; 20(1):e20230009. PMC: 10075188. DOI: 10.1590/1984-3143-AR2023-0009. View

15.

Franklin A, Waddell W, Goodrowe K . Red wolf (Canis rufus) sperm quality and quantity is affected by semen collection method, extender components, and post-thaw holding temperature. Theriogenology. 2018; 116:41-48. DOI: 10.1016/j.theriogenology.2018.05.007. View

16.

Romagnoli N, Zambelli D, Cunto M, Lambertini C, Ventrella D, Baron Toaldo M . Non-invasive evaluation of the haemodynamic effects of high-dose medetomidine in healthy cats for semen collection. J Feline Med Surg. 2015; 18(4):337-43. PMC: 11112246. DOI: 10.1177/1098612X15583345. View

17.

Kutzler M . Semen collection in the dog. Theriogenology. 2005; 64(3):747-54. DOI: 10.1016/j.theriogenology.2005.05.023. View

18.

Diggelmann A, Baron Toaldo M, Bektas R, Furthner E, Reichler I, Kutter A . Atipamezole Reverses Cardiovascular Changes Induced by High-Dose Medetomidine in Cats Undergoing Sedation for Semen Collection. Animals (Basel). 2023; 13(12). PMC: 10295038. DOI: 10.3390/ani13121909. View

19.

da Silva M, Ullony K, de Araujo G, Jorge-Neto P, Albuquerque V, Caramalac S . Can detomidine replace medetomidine for pharmacological semen collection in domestic cats?. Anim Reprod. 2021; 18(2):e20210017. PMC: 8253561. DOI: 10.1590/1984-3143-AR2021-0017. View

20.

Carvalho E, Champion T, Ambrosini F, da Silva G, Freitas G, DOtaviano de Castro Vilani R . Dexmedetomidine low dose followed by constant rate infusion and antagonism by atipamezole in isoflurane-anesthetized cats: an echocardiographic study. Vet Anaesth Analg. 2018; 46(1):43-54. DOI: 10.1016/j.vaa.2018.09.040. View