Chronic Chikungunya Disease (CCD): Clinical Insights, Immunopathogenesis and Therapeutic Perspectives

Overview

Journal QJM

Specialty General Medicine

Date 2024 Feb 20

PMID 38377410

Authors

W H Ng

K Amaral

E Javelle

S Mahalingam

Affiliations

Soon will be listed here.

Abstract

Chikungunya virus, an arthropod-borne pathogen is recognized by the World Health Organization as a top priority Emerging Infectious Disease and is ranked fourth in public health needs according to the Coalition for Epidemic Preparedness Innovations. Despite its substantial impact, as evidenced by an annual estimate of 120 274 disability-adjusted life years, our understanding of the chronic aspects of chikungunya disease remains limited. This review focuses on chronic chikungunya disease, emphasizing its clinical manifestations, immunopathogenesis, therapeutic options and disease burden.

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