Peptidyl-tRNA Hydrolase As a Key Player in the Liberation of Truncated Nascent Chains from the Ribosomal Subunit

Svetlov et al. identify the enzyme peptidyl-tRNA hydrolase as a ribosome-associated quality-control factor that promotes hydrolysis of the dislodged peptidyl-tRNA, which helps to recycle ribosomal subunits blocked by truncated nascent chains in bacteria.