Characterizing Induced Pluripotent Stem Cells and Derived Cardiomyocytes: Insights from Nano Scale Mass Measurements and Mechanical Properties

Overview

Journal Nanoscale Adv

Publisher Royal Society of Chemistry

Specialty Biotechnology

Date 2024 Feb 15

PMID 38356620

Authors

Irene C Turnbull

Angelo Gaitas

Affiliations

Soon will be listed here.

Abstract

Our study reveals that the nano-mechanical measures of elasticity and cell mass change significantly through induced pluripotent stem cell (iPSC) differentiation to cardiomyocytes, providing a reliable method to evaluate such processes. The findings support the importance of identifying these properties, and highlight the potential of AFM for comprehensive characterization of iPSC at the nanoscale.

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