Neurodevelopmental Outcomes of Preterm and Growth-restricted Neonate with Congenital Heart Defect: a Systematic Review and Meta-analysis

Overview

Journal Eur J Pediatr

Specialty Pediatrics

Date 2024 Feb 14

PMID 38353800

Authors

Neil Derridj

Johanna Calderon

Damien Bonnet

Babak Khoshnood

Isabelle Monier

Romain Guedj

Affiliations

Soon will be listed here.

Abstract

Conclusions: Based on a low level of evidence, prematurity and/or growth retardation appear to accentuate specific neurodevelopmental outcomes in certain CHD subgroups. Further evidence is needed to confirm these findings.

Trial Registration: PROSPERO [CRD42020201414].

What Is Known: • Children born with CHD, preterm birth, or growth restriction at birth are independently at higher risk for neurodevelopmental impairment. • The additional effect of preterm birth and/or growth restriction on neurodevelopmental outcomes in children with CHD remains unclear.

What Is New: • Prematurity and/or growth retardation appear to accentuate specific neurodevelopmental outcomes in certain CHD subgroups. • Children with CHD, particularly those born preterm or with growth restriction, should undergo lifelong systematic comprehensive neurodevelopmental assessment.

Citing Articles

[Research progress on neurodevelopmental disorders associated with congenital heart disease].

Liu Y, Liu T, Nong S, Zhou X Zhongguo Dang Dai Er Ke Za Zhi. 2024; 26(11):1231-1237.

PMID: 39587754 PMC: 11601115. DOI: 10.7499/j.issn.1008-8830.2406063.

References

van der Linde D, Konings E, Slager M, Witsenburg M, Helbing W, Takkenberg J . Birth prevalence of congenital heart disease worldwide: a systematic review and meta-analysis. J Am Coll Cardiol. 2011; 58(21):2241-7. DOI: 10.1016/j.jacc.2011.08.025. View

Laas E, Lelong N, Thieulin A, Houyel L, Bonnet D, Ancel P . Preterm birth and congenital heart defects: a population-based study. Pediatrics. 2012; 130(4):e829-37. DOI: 10.1542/peds.2011-3279. View

Petrossian R, Kuehl K, Loffredo C . Relationship of birth weight with congenital cardiovascular malformations in a population-based study. Cardiol Young. 2014; 25(6):1086-92. DOI: 10.1017/S1047951114001644. View

Bellinger D, Wypij D, Rivkin M, DeMaso D, Robertson Jr R, Dunbar-Masterson C . Adolescents with d-transposition of the great arteries corrected with the arterial switch procedure: neuropsychological assessment and structural brain imaging. Circulation. 2011; 124(12):1361-9. PMC: 3217719. DOI: 10.1161/CIRCULATIONAHA.111.026963. View

Hilaire M, Andrianou X, Lenglet A, Ariti C, Charles K, Buitenhuis S . Growth and neurodevelopment in low birth weight versus normal birth weight infants from birth to 24 months, born in an obstetric emergency hospital in Haiti, a prospective cohort study. BMC Pediatr. 2021; 21(1):143. PMC: 7988959. DOI: 10.1186/s12887-021-02605-3. View

Savchev S, Sanz-Cortes M, Cruz-Martinez R, Arranz A, Botet F, Gratacos E . Neurodevelopmental outcome of full-term small-for-gestational-age infants with normal placental function. Ultrasound Obstet Gynecol. 2013; 42(2):201-6. DOI: 10.1002/uog.12391. View

Dong Y, Chen S, Yu J . A systematic review and meta-analysis of long-term development of early term infants. Neonatology. 2012; 102(3):212-21. DOI: 10.1159/000338099. View

Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid A . Rayyan-a web and mobile app for systematic reviews. Syst Rev. 2016; 5(1):210. PMC: 5139140. DOI: 10.1186/s13643-016-0384-4. View

Barendregt J, Doi S, Lee Y, Norman R, Vos T . Meta-analysis of prevalence. J Epidemiol Community Health. 2013; 67(11):974-8. DOI: 10.1136/jech-2013-203104. View

10.

Nyaga V, Arbyn M, Aerts M . Metaprop: a Stata command to perform meta-analysis of binomial data. Arch Public Health. 2015; 72(1):39. PMC: 4373114. DOI: 10.1186/2049-3258-72-39. View

11.

Cheung P, Hajihosseini M, Dinu I, Switzer H, Joffe A, Bond G . Outcomes of Preterm Infants With Congenital Heart Defects After Early Surgery: Defining Risk Factors at Different Time Points During Hospitalization. Front Pediatr. 2021; 8:616659. PMC: 7876369. DOI: 10.3389/fped.2020.616659. View

12.

Heye K, Rousson V, Knirsch W, Beck I, Liamlahi R, Bernet V . Growth and Intellectual Abilities of Six-Year-Old Children with Congenital Heart Disease. J Pediatr. 2018; 204:24-30.e10. DOI: 10.1016/j.jpeds.2018.08.060. View

13.

Butler S, Sadhwani A, Stopp C, Singer J, Wypij D, Dunbar-Masterson C . Neurodevelopmental assessment of infants with congenital heart disease in the early postoperative period. Congenit Heart Dis. 2018; 14(2):236-245. DOI: 10.1111/chd.12686. View

14.

Schultz A, Ittenbach R, Gerdes M, Jarvik G, Wernovsky G, Bernbaum J . Effect of congenital heart disease on 4-year neurodevelopment within multiple-gestation births. J Thorac Cardiovasc Surg. 2017; 154(1):273-281.e2. PMC: 5481170. DOI: 10.1016/j.jtcvs.2017.02.022. View

15.

Sanz J, Berl M, Armour A, Wang J, Cheng Y, Donofrio M . Prevalence and pattern of executive dysfunction in school age children with congenital heart disease. Congenit Heart Dis. 2016; 12(2):202-209. PMC: 5383529. DOI: 10.1111/chd.12427. View

16.

Calderon J, Stopp C, Wypij D, DeMaso D, Rivkin M, Newburger J . Early-Term Birth in Single-Ventricle Congenital Heart Disease After the Fontan Procedure: Neurodevelopmental and Psychiatric Outcomes. J Pediatr. 2016; 179:96-103. DOI: 10.1016/j.jpeds.2016.08.084. View

17.

Simons J, Sood E, Derby C, Pizarro C . Predictive value of near-infrared spectroscopy on neurodevelopmental outcome after surgery for congenital heart disease in infancy. J Thorac Cardiovasc Surg. 2011; 143(1):118-25. DOI: 10.1016/j.jtcvs.2011.09.007. View

18.

Pappas A, Shankaran S, Hansen N, Bell E, Stoll B, Laptook A . Outcome of extremely preterm infants (<1,000 g) with congenital heart defects from the National Institute of Child Health and Human Development Neonatal Research Network. Pediatr Cardiol. 2012; 33(8):1415-26. PMC: 3687358. DOI: 10.1007/s00246-012-0375-8. View

19.

Newburger J, Sleeper L, Bellinger D, Goldberg C, Tabbutt S, Lu M . Early developmental outcome in children with hypoplastic left heart syndrome and related anomalies: the single ventricle reconstruction trial. Circulation. 2012; 125(17):2081-91. PMC: 3341507. DOI: 10.1161/CIRCULATIONAHA.111.064113. View

20.

Goff D, Luan X, Gerdes M, Bernbaum J, DAgostino J, Rychik J . Younger gestational age is associated with worse neurodevelopmental outcomes after cardiac surgery in infancy. J Thorac Cardiovasc Surg. 2012; 143(3):535-42. PMC: 4423823. DOI: 10.1016/j.jtcvs.2011.11.029. View