Antibacterial Activity of Plant Extracts Against Subsp. Isolates from Guinea Pigs with Lymphadenitis in Ecuador

Overview

Journal Heliyon

Specialty Social Sciences

Date 2024 Feb 14

PMID 38352743

Authors

Yadira F Ordonez

Estefania Miranda

Maria Fernanda Lopez

Paola E Ordonez

Affiliations

Soon will be listed here.

Abstract

Lymphadenitis is a commonly occurring and contagious disease in guinea pigs caused by different pathogens, including sp., sp., and sp. This study aimed to characterize the bacteria isolated from pus extracted from abscessed mandibular lymph nodes of diseased guinea pigs in Ecuador in 2019 and evaluate the in vitro antibacterial activity of the total extracts of three plant species. Isolates were recovered from three diseased guinea pigs with Lymphadenitis on a farm in Imbabura, Ecuador province. The bacteria were characterized through microbiological, biochemical, and molecular tests as subsp. . Furthermore, the susceptibility of subsp. to three plant extracts belonging to the Asteraceae family, collected in Ecuador, were assessed in vitro by the microdilution method. Our data indicate that all the evaluated extracts showed activity, with a Minimum Inhibitory Concentration (MIC) of 22.50 mg/mL for , 11.25 mg/mL for , and 5.60 mg/mL for . extract showed the highest efficacy with a % inhibition of 63.90 at the highest tested concentration (45 mg/mL). This is the first report on the bioactivity of these plant species against subsp. .

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