Exploring the Impact of Glycemic Control on Diabetic Retinopathy: Emerging Models and Prognostic Implications

Overview

Journal J Clin Med

Specialty General Medicine

Date 2024 Feb 10

PMID 38337523

Authors

Nicola Tecce

Gilda Cennamo

Michele Rinaldi

Ciro Costagliola

Annamaria Colao

Affiliations

Soon will be listed here.

Abstract

This review addresses the complexities of type 1 diabetes (T1D) and its associated complications, with a particular focus on diabetic retinopathy (DR). This review outlines the progression from non-proliferative to proliferative diabetic retinopathy and diabetic macular edema, highlighting the role of dysglycemia in the pathogenesis of these conditions. A significant portion of this review is devoted to technological advances in diabetes management, particularly the use of hybrid closed-loop systems (HCLSs) and to the potential of open-source HCLSs, which could be easily adapted to different patients' needs using big data analytics and machine learning. Personalized HCLS algorithms that integrate factors such as patient lifestyle, dietary habits, and hormonal variations are highlighted as critical to reducing the incidence of diabetes-related complications and improving patient outcomes.

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