Prone Positioning in Acute Respiratory Distress Syndrome

Overview

Journal NEJM Evid

Specialty General Medicine

Date 2024 Feb 6

PMID 38319184

Authors

Alex K Pearce

W Cameron McGuire

Atul Malhotra

Affiliations

Soon will be listed here.

Abstract

Prone Positioning in ARDSCovid-19 has greatly expanded the use of prone positioning for patients with respiratory failure. Pearce and colleagues review the physiology of prone positioning and the evidence for its use, including in nonintubated patients.

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References

Sud S, Friedrich J, Adhikari N, Taccone P, Mancebo J, Polli F . Effect of prone positioning during mechanical ventilation on mortality among patients with acute respiratory distress syndrome: a systematic review and meta-analysis. CMAJ. 2014; 186(10):E381-90. PMC: 4081236. DOI: 10.1503/cmaj.140081. View

Albert R, Hubmayr R . The prone position eliminates compression of the lungs by the heart. Am J Respir Crit Care Med. 2000; 161(5):1660-5. DOI: 10.1164/ajrccm.161.5.9901037. View

Mackenzie C . Anatomy, physiology, and pathology of the prone position and postural drainage. Crit Care Med. 2001; 29(5):1084-5. DOI: 10.1097/00003246-200105000-00046. View

DOUGLAS W, REHDER K, Beynen F, SESSLER A, Marsh H . Improved oxygenation in patients with acute respiratory failure: the prone position. Am Rev Respir Dis. 1977; 115(4):559-66. DOI: 10.1164/arrd.1977.115.4.559. View

Moss M, Ulysse C, Angus D . Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome. Reply. N Engl J Med. 2019; 381(8):787-788. DOI: 10.1056/NEJMc1908874. View

Scaramuzzo G, Gamberini L, Tonetti T, Zani G, Ottaviani I, Mazzoli C . Sustained oxygenation improvement after first prone positioning is associated with liberation from mechanical ventilation and mortality in critically ill COVID-19 patients: a cohort study. Ann Intensive Care. 2021; 11(1):63. PMC: 8072095. DOI: 10.1186/s13613-021-00853-1. View

Mancebo J, Fernandez R, Blanch L, Rialp G, Gordo F, Ferrer M . A multicenter trial of prolonged prone ventilation in severe acute respiratory distress syndrome. Am J Respir Crit Care Med. 2006; 173(11):1233-9. DOI: 10.1164/rccm.200503-353OC. View

Beuret P . Prone position for the prevention of lung infection. Minerva Anestesiol. 2002; 68(4):266-8. View

Ware L, Matthay M . Clinical practice. Acute pulmonary edema. N Engl J Med. 2005; 353(26):2788-96. DOI: 10.1056/NEJMcp052699. View

10.

Beitler J, Shaefi S, Montesi S, Devlin A, Loring S, Talmor D . Prone positioning reduces mortality from acute respiratory distress syndrome in the low tidal volume era: a meta-analysis. Intensive Care Med. 2014; 40(3):332-41. PMC: 3976426. DOI: 10.1007/s00134-013-3194-3. View

11.

Gattinoni L, Coppola S, Cressoni M, Busana M, Rossi S, Chiumello D . COVID-19 Does Not Lead to a "Typical" Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2020; 201(10):1299-1300. PMC: 7233352. DOI: 10.1164/rccm.202003-0817LE. View

12.

Cherian S, Kumar A, Akasapu K, Ashton R, Aparnath M, Malhotra A . Salvage therapies for refractory hypoxemia in ARDS. Respir Med. 2018; 141:150-158. PMC: 6186150. DOI: 10.1016/j.rmed.2018.06.030. View

13.

Guerin C, Reignier J, Richard J, Beuret P, Gacouin A, Boulain T . Prone positioning in severe acute respiratory distress syndrome. N Engl J Med. 2013; 368(23):2159-68. DOI: 10.1056/NEJMoa1214103. View

14.

Cotton S, Roche C, Malhotra A . Proning During COVID-19: The Importance of Teamwork. Am J Crit Care. 2020; 29(6):418. PMC: 7716276. DOI: 10.4037/ajcc2020542. View

15.

Munshi L, Del Sorbo L, Adhikari N, Hodgson C, Wunsch H, Meade M . Prone Position for Acute Respiratory Distress Syndrome. A Systematic Review and Meta-Analysis. Ann Am Thorac Soc. 2017; 14(Supplement_4):S280-S288. DOI: 10.1513/AnnalsATS.201704-343OT. View

16.

Gattinoni L, Pesenti A . The concept of "baby lung". Intensive Care Med. 2005; 31(6):776-84. DOI: 10.1007/s00134-005-2627-z. View

17.

Wiedemann H, Wheeler A, Bernard G, Thompson B, Hayden D, deBoisblanc B . Comparison of two fluid-management strategies in acute lung injury. N Engl J Med. 2006; 354(24):2564-75. DOI: 10.1056/NEJMoa062200. View

18.

Sarge T, Baedorf-Kassis E, Banner-Goodspeed V, Novack V, Loring S, Gong M . Effect of Esophageal Pressure-guided Positive End-Expiratory Pressure on Survival from Acute Respiratory Distress Syndrome: A Risk-based and Mechanistic Reanalysis of the EPVent-2 Trial. Am J Respir Crit Care Med. 2021; 204(10):1153-1163. PMC: 8759303. DOI: 10.1164/rccm.202009-3539OC. View

19.

Agostoni E, DAngelo E, BONANNI M . The effect of the abdomen on the vertical gradient of pleural surface pressure. Respir Physiol. 1970; 8(3):332-46. DOI: 10.1016/0034-5687(70)90040-x. View

20.

Albert R . Prone position in ARDS: what do we know, and what do we need to know?. Crit Care Med. 1999; 27(11):2574-5. DOI: 10.1097/00003246-199911000-00044. View