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Tracheal Resection Anastomosis for Rare Tracheal Inflammatory Lesions Mimicking Malignancy: Report of 2 Cases

Abstract

Background: Tumor-like lesions of the trachea are rare and challenging in diagnosis and management. Inflammatory myofibroblastoma, also known as Inflammatory pseudo tumors (IPTs), as well as Rosai Dorfman Disease (RDD) are inflammatory lesions that may involve the central airways with variable non-specific clinical features mimicking tumors.

Case Presentation: In this study 2 cases with tumor-like lesions are presented. One case with an inflammatory pseudotumor and the other one with Rosai-Dorfman disease affecting the upper trachea. Both cases were successfully managed with tracheal resection anastomosis.

Conclusion: Tracheal Inflammatory myofibroblastoma, and Rosai-Dorfman diseases are rare tumor like lesions that present with upper airway obstruction. Despite being benign, these lesions may have features suggestive of malignancy, requiring prompt management. Complete surgical excision by segmental resection and primary anastomosis (if feasible) is the treatment of choice with an optimum outcome.

References
1.
DESTOMBES P . [Adenitis with lipid excess, in children or young adults, seen in the Antilles and in Mali. (4 cases)]. Bull Soc Pathol Exot Filiales. 1965; 58(6):1169-75. View

2.
Boissiere L, Patey M, Toubas O, Vella-Boucaud J, Perotin-Collard J, Deslee G . Tracheobronchial Involvement of Rosai-Dorfman Disease: Case Report and Review of the Literature. Medicine (Baltimore). 2016; 95(7):e2821. PMC: 4998634. DOI: 10.1097/MD.0000000000002821. View

3.
Ebada H, Abd El-Fattah A, Salem E, Elkotb M, Kamal E, Tawfik A . Challenging tracheal resection anastomosis: Case series. Auris Nasus Larynx. 2020; 47(4):616-623. DOI: 10.1016/j.anl.2020.01.004. View

4.
Ozturk S, Kutlay H, Sak S, Yavuzer S . Fibrohistiocytic tumor of the trachea in a child. Eur J Cardiothorac Surg. 1999; 16(4):464-8. DOI: 10.1016/s1010-7940(99)00288-2. View

5.
. Histiocytosis syndromes in children. Writing Group of the Histiocyte Society. Lancet. 1987; 1(8526):208-9. View