Rapid Assessment of Di(2-ethylhexyl) Phthalate Migration from Consumer PVC Products

Overview

Journal Toxics

Date 2024 Jan 26

PMID 38276720

Authors

Jiwon An

Hyun-Ho Roh

Haeyoon Jeong

Kuen-Yong Lee

Taiyoun Rhim

Affiliations

Soon will be listed here.

Abstract

Poly(vinyl chloride) (PVC) is widely used to produce various consumer goods, including food packaging, toys for children, building materials, and cosmetic products. However, despite their widespread use, phthalate plasticizers have been identified as endocrine disruptors, which cause adverse health effects, thus leading to increasing concerns regarding their migration from PVC products to the environment. This study proposed a method for rapidly measuring the migration of phthalates, particularly di(2-ethylhexyl) phthalate (DEHP), from PVC products to commonly encountered liquids. The release of DEHP under various conditions, including exposure to aqueous and organic solvents, different temperatures, and household microwaves, was investigated. The amount of DEHP released from both laboratory-produced PVC films and commercially available PVC products was measured to elucidate the potential risks associated with its real-world applications. Furthermore, tests were performed to evaluate cytotoxicity using estrogen-dependent and -independent cancer cell lines. The results revealed a dose-dependent impact on estrogen-dependent cells, thus emphasizing the potential health implications of phthalate release. This comprehensive study provides valuable insights into the migration patterns of DEHP from PVC products and forms a basis for further research on the safety of PVC and plasticizers.

Citing Articles

Significance of Morphology in Characterizing Human Health Risk from di(2-ethylhexyl) Phthalate in Polyvinyl Chloride Microplastics in Groundwater.

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Phthalate Acid Esters (PAEs) in Indoor Dust from Decoration Material Stores: Occurrence, Sources, and Health Risks.

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