» Articles » PMID: 38274772

Current Scientific Evidence for Why Periodontitis Should Be Included in Diabetes Management

Overview
Specialty Endocrinology
Date 2024 Jan 26
PMID 38274772
Authors
Affiliations
Soon will be listed here.
Abstract

This Perspective provides a brief summary of the scientific evidence for the two-way links between periodontal diseases and hyperglycemia (diabetes mellitus [DM] and pre-DM). It delivers in a nutshell current scientific evidence for manifestations of hyperglycemia on periodontal health status and effects of periodontal diseases on blood glucose levels and in turn incidence, progression, and complications of diabetes. Of outmost importance is presentation of scientific evidence for the potential of routine periodontal treatment to lower blood glucose levels, providing a novel, economical tool in DM management. Non-surgical periodontal treatment ("deep cleaning") can be provided by dental hygienists or dentists in general dental offices, although severe cases should be referred to specialists. Such therapy can decrease the costs of DM care and other health care costs for people with DM. The great importance of a healthy oral cavity free of infection and subsequent inflammation - especially periodontitis that if untreated will cause loosening and eventually loss of affected teeth - has largely gone unnoticed by the medical community as the health care curricula are largely void of content regarding the bi-directional links between oral health and systemic health, despite elevation of blood glucose levels being an integral part of the general systemic inflammation response. The importance of keeping disease-free, natural teeth for proper biting and chewing, smiling, self-esteem, and pain avoidance cannot be overestimated. Medical and dental professionals are strongly encouraged to collaborate in patient-centered care for their mutual patients with - or at risk for - hyperglycemia.

Citing Articles

A Three-Month Clinical Trial on the Efficacy of Hyaluronic Acid Adjunctive Non-Surgical Therapy for Periodontitis in Patients with Type 2 Diabetes Mellitus.

Olszewska-Czyz I, Michalak E, Dudzik A Biomedicines. 2024; 12(11).

PMID: 39595081 PMC: 11591565. DOI: 10.3390/biomedicines12112516.


Periodontal disease: A silent factor in the development and progression of diabetic retinopathy.

Lomeli Martinez S, Cortes Trujillo I, Martinez Nieto M, Mercado Gonzalez A World J Diabetes. 2024; 15(8):1672-1676.

PMID: 39192852 PMC: 11346087. DOI: 10.4239/wjd.v15.i8.1672.


Pathology of Diabetes-Induced Immune Dysfunction.

Alexander M, Cho E, Gliozheni E, Salem Y, Cheung J, Ichii H Int J Mol Sci. 2024; 25(13).

PMID: 39000211 PMC: 11241249. DOI: 10.3390/ijms25137105.

References
1.
Herman W, Taylor G, Jacobson J, Burke R, Brown M . Screening for prediabetes and type 2 diabetes in dental offices. J Public Health Dent. 2015; 75(3):175-82. PMC: 5053230. DOI: 10.1111/jphd.12082. View

2.
Su Y, Ye L, Hu C, Zhang Y, Liu J, Shao L . Periodontitis as a promoting factor of T2D: current evidence and mechanisms. Int J Oral Sci. 2023; 15(1):25. PMC: 10272210. DOI: 10.1038/s41368-023-00227-2. View

3.
Lafleur S, Bodein A, Mbuya Malaika Mutombo J, Mathieu A, Joly Beauparlant C, Minne X . Multi-Omics Data Integration Reveals Key Variables Contributing to Subgingival Microbiome Dysbiosis-Induced Inflammatory Response in a Hyperglycemic Microenvironment. Int J Mol Sci. 2023; 24(10). PMC: 10218861. DOI: 10.3390/ijms24108832. View

4.
Cardenas K, Weilnau T, Aguilar C, Ali A, Eidelman A, Ponnala S . Partnering for Integrated Care: A Learning Collaborative for Primary Care and Oral Health Teams. Ann Fam Med. 2023; 21(Suppl 2):S22-S30. PMC: 9970677. DOI: 10.1370/afm.2918. View

5.
Chen Y, Zhan Q, Wu C, Yuan Y, Chen W, Yu F . Baseline HbA1c Level Influences the Effect of Periodontal Therapy on Glycemic Control in People with Type 2 Diabetes and Periodontitis: A Systematic Review on Randomized Controlled Trails. Diabetes Ther. 2021; 12(5):1249-1278. PMC: 8099950. DOI: 10.1007/s13300-021-01000-6. View