Case Report: Occult Invasion Leading to Prosthetic Hip Joint Infection in a Patient with Rheumatoid Arthritis Taking Tofacitinib

Overview

Journal Front Med (Lausanne)

Specialty General Medicine

Date 2024 Jan 24

PMID 38264038

Authors

Chaowen Deng

Kelvin Hei-Yeung Chiu

Nan Lou

Fanfan Xing

Affiliations

Soon will be listed here.

Abstract

It has been suggested that targeted therapy may potentially increase the risk of listeriosis. However, no reported cases of prosthetic joint infection have been documented during Janus Kinase (JAK) pathway inhibitor use. Herein, we present a 70-year-old female with rheumatoid arthritis who had undergone bilateral hip joint replacement and subsequently developed prosthetic joint infection following tofacitinib therapy. We suggest that the use of tofacitinib may potentially heighten susceptibility to listeriosis in patients afflicted with rheumatoid arthritis.

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