One-Day Interruption of NOAC Is Associated with Low Risk of Periprocedural Adverse Events During Pulmonary Vein Isolation If Combined with Left Atrial Thrombus Exclusion with Computed Tomography

Overview

Journal Life (Basel)

Specialty Biology

Date 2024 Jan 23

PMID 38255747

Authors

Katalin Piros

Adorjan Vida

Nandor Szegedi

Peter Perge

Zoltan Sallo

Arnold Bela Ferencz

Vivien Klaudia Nagy

Szilvia Herczeg

Pal Abraham

Csaba Csobay-Novak

Zsofia Drobni

Tamas Tahin

Gyorgyi Apponyi

Bela Merkely

Laszlo Geller

Istvan Osztheimer

Affiliations

Soon will be listed here.

Abstract

Background: Safety, efficacy, and patient comfort are the expectations during pulmonary vein isolation (PVI). We aimed to validate the combined advantages of pre- and periprocedural anticoagulation with non-vitamin K anticoagulants (NOACs) and rigorous left atrial appendage thrombus (LAAT) exclusion with computed tomography (CT).

Methods: This study included a population of consecutive patients, between March 2018 and June 2020, who underwent cardiac CT within 24 h before PVI to guide the ablation and rule out LAAT. NOAC was omitted 24 h before the ablation.

Results: A total of 187 patients (63% male) underwent CT before PVI. None of the patients experienced stroke during or after the procedure. The complication rate was low, with no thromboembolic events and 2.1% of patients experiencing a major bleeding event.

Conclusions: Omitting NOAC 24 h before the ablation might be safe if combined with left atrial thrombus exclusion with computed tomography.

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