Mechanisms of Epigenetic Inheritance in Post-Traumatic Stress Disorder

Overview

Journal Life (Basel)

Specialty Biology

Date 2024 Jan 23

PMID 38255713

Authors

Pei-Chen Chou

Yu-Chi Huang

Sebastian Yu

Affiliations

Soon will be listed here.

Abstract

Post-traumatic stress disorder (PTSD) is a psychiatric disorder that causes debilitating functional impairment in patients. Observations from survivors of traumatic historical events solidify that this disease is not only associated with personal experiences but can also be inherited from familial traumas. Over the past decades, researchers have focused on epigenetic inheritance to understand how responses to adverse experiences can be passed down to future generations. This review aims to present recent findings on epigenetic markers related to PTSD and research in the intergenerational inheritance of trauma. By understanding the information, we hope that epigenetic markers can act as biochemical measurements for future clinical practice.

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