Recent Advances in Quaternary Ammonium Monomers for Dental Applications

Overview

Journal Materials (Basel)

Publisher MDPI

Date 2024 Jan 23

PMID 38255513

Authors

Xiaoxu Liang

Biao Yu

Liuqi Ye

Danlei Lin

Wen Zhang

Hai-Jing Zhong

Jingwei He

Affiliations

Soon will be listed here.

Abstract

Resin-based dental materials have been one of the ideal choices among various materials in the treatment of dental caries. However, resin-based dental materials still have some drawbacks, such as the lack of inherent antibacterial activity. Extensive research has been conducted on the use of novel quaternary ammonium monomers (QAMs) to impart antibacterial activity to dental materials. This review provides a comprehensive overview of the recent advances in quaternary ammonium monomers (QAMs) for dental applications. The current progress and limitations of QAMs are discussed based on the evolution of their structures. The functional diversification and enhancement of QAMs are presented. QAMs have the potential to provide long-term antibacterial activity in dental resin composites, thereby prolonging their service life. However, there is a need to balance antibacterial performance with other material properties and the potential impact on the oral microbiome and general health. Finally, the necessity for further scientific progress in the development of novel quaternary ammonium monomers and the optimization of dental resin formulations is emphasized.

Citing Articles

Novel Resin-Based Antibacterial Root Surface Coating Material to Combat Dental Caries.

Almutairi N, Alhussein A, Alenizy M, Ba-Armah I, Sun J, Weir M J Funct Biomater. 2024; 15(6).

PMID: 38921541 PMC: 11204561. DOI: 10.3390/jfb15060168.

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