CuO Nanoparticles for Green Synthesis of Significant Anti-Helicobacter Pylori Compounds with in Silico Studies

Overview

Journal Sci Rep

Specialty Science

Date 2024 Jan 18

PMID 38238369

Authors

Wesam S Shehab

Doaa A Elsayed

Atef M Abdel Hamid

Mohamed G Assy

Samar M Mouneir

Eman O Hamed

Sahar M Mousa

Gehan T El-Bassyouni

Affiliations

Soon will be listed here.

Abstract

Helicobacter pylori (H. pylori) is a universal health intimidation as mentioned by the World Health Organization. The primary causal agent linked to a number of illnesses, including inflammation and the development of stomach ulcers, is Helicobacter pylori. Since, H. pylori develops antibiotic resistance quickly, current H. pylori treatment approaches are becoming less effective. Our research aims to highlight novel formulation antibiotics using CuO-NPs as catalysts and studied their activity as anti-helicobacter pylori supported by computational studies (POM analysis and molecular docking) software. They were designed for anti-Helicobacter Pylori action. All compounds revealed a bactericidal effect better than the reference McFarland standards.

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