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Disturbance of Growth in Pediatric Patients Due to Osteomyelitis Caused by Growth Plate Infection

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Journal Cureus
Date 2024 Jan 16
PMID 38226077
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Abstract

Osteomyelitis, a severe bone infection, poses a multifaceted challenge to healthcare professionals. While its pathophysiology and treatment have been extensively studied, the impact of osteomyelitis on skeletal growth, particularly in pediatric patients, is an area that warrants attention. This abstract highlights the significance of understanding and managing growth disturbances in osteomyelitis, providing key findings and recommendations for clinicians. Understanding growth disturbance in osteomyelitis is essential because it can lead to lifelong consequences for pediatric patients. The infection may affect the growth plate, leading to limb length discrepancies, angular deformities, and functional impairments. These complications not only diminish the quality of life but also pose a substantial economic burden on the healthcare system. Therefore, early recognition and intervention are crucial. Key findings indicate that the risk of growth disturbances in osteomyelitis is particularly high in pediatric patients due to the vulnerability of the growth plate. Timely diagnosis, appropriate management, and targeted interventions can mitigate the long-term sequelae of growth disturbances. These include utilizing advanced imaging techniques to assess the extent of growth plate involvement, optimizing antibiotic therapy, and employing surgical techniques like epiphysiodesis, guided growth, or corrective osteotomies. Additionally, fostering a multidisciplinary approach that involves orthopedic surgeons, infectious disease specialists, and pediatric endocrinologists is vital to achieving successful outcomes. Recommendations for managing growth disturbance in osteomyelitis encompass early detection, meticulous monitoring, and a tailored treatment plan. Healthcare providers should remain vigilant for signs of growth plate involvement in osteomyelitis patients, especially in the pediatric population. A thorough evaluation, including advanced imaging and clinical assessment, is essential for accurate diagnosis. Close collaboration between specialists to address the infection and its skeletal consequences is crucial. Furthermore, patient and family education plays a pivotal role in fostering compliance with the treatment regimen. In conclusion, understanding and managing growth disturbances in osteomyelitis is paramount, particularly in pediatric patients. The implications of growth plate involvement are significant, and timely intervention is essential to prevent lifelong consequences. By implementing a comprehensive approach that combines accurate diagnosis, multidisciplinary collaboration, and patient education, healthcare professionals can enhance the quality of life and well-being of those affected by this challenging condition.

References
1.
El Houmami N, Minodier P, Bouvier C, Seligmann H, Jouve J, Raoult D . Primary subacute epiphyseal osteomyelitis caused by Mycobacterium species in young children: a modern diagnostic approach. Eur J Clin Microbiol Infect Dis. 2017; 36(5):771-777. DOI: 10.1007/s10096-016-2886-3. View

2.
Funk S, Copley L . Acute Hematogenous Osteomyelitis in Children: Pathogenesis, Diagnosis, and Treatment. Orthop Clin North Am. 2017; 48(2):199-208. DOI: 10.1016/j.ocl.2016.12.007. View

3.
Kaziz H, Amine Triki M, Chermiti W, Mouelhi T, Naouar N, Laziz Ben Ayeche M . Acute osteomyelitis of the distal fibula in children: Treatment options and long-term follow-up. Arch Pediatr. 2020; 27(6):342-347. DOI: 10.1016/j.arcped.2020.06.010. View

4.
Ottaviani G, Jaffe N . The etiology of osteosarcoma. Cancer Treat Res. 2010; 152:15-32. DOI: 10.1007/978-1-4419-0284-9_2. View

5.
Urish K, Cassat J . Staphylococcus aureus Osteomyelitis: Bone, Bugs, and Surgery. Infect Immun. 2020; 88(7). PMC: 7309607. DOI: 10.1128/IAI.00932-19. View