The Multi-dimensional Challenge of Poor Oral Health in Cirrhosis-Disparities and Solutions

Overview

Journal Gastroenterology

Specialty Gastroenterology

Date 2024 Jan 15

PMID 38224859

Authors

Mette M Lauridsen

Lea L Gronkjaer

Sara Khraibut

Nilang Patel

Janina Golob Deeb

Jasmohan S Bajaj

Affiliations

Soon will be listed here.

Citing Articles

Analysis of Oral and Gut Microbiome Composition and Its Impact in Patients with Oral Squamous Cell Carcinoma.

Matsui K, Tani R, Yamasaki S, Ito N, Hamada A, Shintani T Int J Mol Sci. 2024; 25(11).

PMID: 38892262 PMC: 11172797. DOI: 10.3390/ijms25116077.

References

Teeuw W, Slot D, Susanto H, Gerdes V, Abbas F, DAiuto F . Treatment of periodontitis improves the atherosclerotic profile: a systematic review and meta-analysis. J Clin Periodontol. 2013; 41(1):70-9. DOI: 10.1111/jcpe.12171. View

Gronkjaer L, Vilstrup H . Oral health in patients with liver cirrhosis. Eur J Gastroenterol Hepatol. 2015; 27(7):834-9. DOI: 10.1097/MEG.0000000000000356. View

Bajaj J, Lai J, Tandon P, OLeary J, Wong F, Garcia-Tsao G . Role of Oral Health, Frailty, and Minimal Hepatic Encephalopathy in the Risk of Hospitalization: A Prospective Multi-Center Cohort of Outpatients With Cirrhosis. Clin Gastroenterol Hepatol. 2022; 21(7):1864-1872.e2. PMC: 11057906. DOI: 10.1016/j.cgh.2022.10.023. View

Aberg F, Helenius-Hietala J, Meurman J, Isoniemi H . Association between dental infections and the clinical course of chronic liver disease. Hepatol Res. 2013; 44(3):349-53. DOI: 10.1111/hepr.12126. View

Quinonez C, Jones J, Vujicic M, Tomar S, Lee J . The 2021 report on oral health in America: Directions for the future of dental public health and the oral health care system. J Public Health Dent. 2022; 82(2):133-137. DOI: 10.1111/jphd.12521. View

Toniazzo M, Amorim P, Muniz F, Weidlich P . Relationship of nutritional status and oral health in elderly: Systematic review with meta-analysis. Clin Nutr. 2017; 37(3):824-830. DOI: 10.1016/j.clnu.2017.03.014. View

Bajaj J, Matin P, White M, Fagan A, Deeb J, Acharya C . Periodontal therapy favorably modulates the oral-gut-hepatic axis in cirrhosis. Am J Physiol Gastrointest Liver Physiol. 2018; 315(5):G824-G837. PMC: 6293251. DOI: 10.1152/ajpgi.00230.2018. View

Bajaj J, Wade J, Gibson D, Heuman D, Thacker L, Sterling R . The multi-dimensional burden of cirrhosis and hepatic encephalopathy on patients and caregivers. Am J Gastroenterol. 2011; 106(9):1646-53. PMC: 3989143. DOI: 10.1038/ajg.2011.157. View

Gronkjaer L, Holmstrup P, Jepsen P, Vilstrup H . The impact of oral diseases in cirrhosis on complications and mortality. JGH Open. 2021; 5(2):294-300. PMC: 7857277. DOI: 10.1002/jgh3.12489. View

10.

Albillos A, Martin-Mateos R, van der Merwe S, Wiest R, Jalan R, Alvarez-Mon M . Cirrhosis-associated immune dysfunction. Nat Rev Gastroenterol Hepatol. 2021; 19(2):112-134. DOI: 10.1038/s41575-021-00520-7. View

11.

Desai A, Mohan P, Nokes B, Sheth D, Knapp S, Boustani M . Increasing Economic Burden in Hospitalized Patients With Cirrhosis: Analysis of a National Database. Clin Transl Gastroenterol. 2019; 10(7):e00062. PMC: 6708673. DOI: 10.14309/ctg.0000000000000062. View

12.

Bajaj J, Betrapally N, Hylemon P, Heuman D, Daita K, White M . Salivary microbiota reflects changes in gut microbiota in cirrhosis with hepatic encephalopathy. Hepatology. 2015; 62(4):1260-71. PMC: 4587995. DOI: 10.1002/hep.27819. View

13.

Horner-Johnson W, Dobbertin K, Beilstein-Wedel E . Disparities in dental care associated with disability and race and ethnicity. J Am Dent Assoc. 2015; 146(6):366-74. DOI: 10.1016/j.adaj.2015.01.024. View

14.

Kardashian A, Serper M, Terrault N, Nephew L . Health disparities in chronic liver disease. Hepatology. 2022; 77(4):1382-1403. PMC: 10026975. DOI: 10.1002/hep.32743. View

15.

Gronkjaer L, Holmstrup P, Schou S, Kongstad J, Jepsen P, Vilstrup H . Periodontitis in patients with cirrhosis: a cross-sectional study. BMC Oral Health. 2018; 18(1):22. PMC: 5811961. DOI: 10.1186/s12903-018-0487-5. View

16.

Bagan J, Alapont L, Sanz C, del Olmo J, Morcillo E, Cortijo J . [Dental and salivary alterations in patients with liver cirrhosis: a study of 100 cases]. Med Clin (Barc). 1998; 111(4):125-8. View

17.

Jones P, Lai J, Bajaj J, Kanwal F . Actionable Solutions to Achieve Health Equity in Chronic Liver Disease. Clin Gastroenterol Hepatol. 2023; 21(8):1992-2000. PMC: 10330625. DOI: 10.1016/j.cgh.2023.03.043. View

18.

Bajaj J, Choudhury A, Xie Q, Kamath P, Topazian M, Hayes P . Global disparities in mortality and liver transplantation in hospitalised patients with cirrhosis: a prospective cohort study for the CLEARED Consortium. Lancet Gastroenterol Hepatol. 2023; 8(7):611-622. PMC: 10330833. DOI: 10.1016/S2468-1253(23)00098-5. View

19.

Guggenheimer J, Eghtesad B, Close J, Shay C, Fung J . Dental health status of liver transplant candidates. Liver Transpl. 2007; 13(2):280-6. DOI: 10.1002/lt.21038. View

20.

Acharya C, Sahingur S, Bajaj J . Microbiota, cirrhosis, and the emerging oral-gut-liver axis. JCI Insight. 2017; 2(19). PMC: 5841881. DOI: 10.1172/jci.insight.94416. View