The Oncolytic Activity of Zika Viral Therapy in Human Neuroblastoma In Vivo Models Confers a Major Survival Advantage in a CD24-dependent Manner

Overview

Journal Cancer Res Commun

Specialty Oncology

Date 2024 Jan 12

PMID 38214542

Authors

Joseph Mazar

Jeanne K Brooks

Matthew Peloquin

Rosa Rosario

Emma Sutton

Matthew Longo

Dennis Drehner

Tamarah J Westmoreland

Affiliations

Soon will be listed here.

Abstract

Significance: Sensitivity to the tumoricidal effect of ZIKV on high-risk neuroblastoma tumors is dependent on CD24 expression, offering a prognostic marker for this oncolytic therapy in an extensive array of CD24-expressing cancers.

Citing Articles

Neuroblastoma-A Review of Combination Immunotherapy.

Pieniazek B, Cencelewicz K, Bzdziuch P, Mlynarczyk L, Lejman M, Zawitkowska J Int J Mol Sci. 2024; 25(14).

PMID: 39062971 PMC: 11276848. DOI: 10.3390/ijms25147730.

Zika Virus: A Neurotropic Warrior against High-Grade Gliomas-Unveiling Its Potential for Oncolytic Virotherapy.

Calderon-Pelaez M, Maradei Anaya S, Bedoya-Rodriguez I, Gonzalez-Ipuz K, Vera-Palacios D, Buitrago I Viruses. 2024; 16(4).

PMID: 38675903 PMC: 11055012. DOI: 10.3390/v16040561.

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