The Association Between Phthalate Exposure and Pubertal Development
Overview
Affiliations
Conclusions: Our results suggest that phthalate exposure, especially exposure to the HMWP, may have inverse association with male pubertal development. Further investigation is required to verify the relationship of phthalate exposure and pubertal development in girls.
What Is Known: • Exposure to phthalates may have antiandrogenic effects. • Studies on the association between phthalates and pubertal development have yielded inconsistent results.
What Is New: • Phthalate levels were inversely associated with self-reported pubertal stages in boys. • Exposure to phthalates might have a negative influence on male pubertal development.
The role of MicroRNAs as fine-tuners in the onset of puberty: a comprehensive review.
Jeong H, Hwang I Ann Pediatr Endocrinol Metab. 2024; 29(4):211-219.
PMID: 39231482 PMC: 11374517. DOI: 10.6065/apem.2346238.119.