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Relationship Between Cardiometabolic Index in Early Pregnancy and Hypertensive Disorder Complicating Pregnancy

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Journal Cureus
Date 2024 Jan 11
PMID 38205084
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Abstract

Background This study aimed to examine the cardiometabolic index during early pregnancy in individuals with hypertension-complicating pregnancy, especially preeclampsia. Additionally, this study sought to determine the relationship between cardiometabolic index and the incidence of varying degrees of preeclampsia. Methodology This study included 289 pregnant women diagnosed with preeclampsia who were registered and delivered at our hospital. These women were assigned to the preeclampsia group. Additionally, a group of 289 healthy pregnant women of identical gestational ages within the same time frame was included for comparison. Clinical data on pregnancy, including body mass index (BMI), blood pressure, waistline, triglyceride levels, and cardiometabolic index, were compared between the two groups. An analysis was conducted to examine the association between early pregnancy cardiometabolic index and the occurrence of preeclampsia. Results There was a significant association between the quartile of cardiometabolic index and the proportion of preeclampsia patients (p < 0.001). Furthermore, after controlling for age and BMI, the risk of preeclampsia remained significantly elevated and was associated with the cardiometabolic index. Conclusions A positive correlation was observed between cardiometabolic index during early pregnancy and the occurrence of preeclampsia.

References
1.
Chen H, Qian N, Yan L, Jiang H . Role of serum vitamin A and E in pregnancy. Exp Ther Med. 2018; 16(6):5185-5189. PMC: 6257734. DOI: 10.3892/etm.2018.6830. View

2.
Chen W, Guo Y, Yao X, Zhao D . Correlation of Blood Lipid and Serum Inflammatory Factor Levels With Hypertensive Disorder Complicating Pregnancy. Front Surg. 2022; 9:917458. PMC: 9249135. DOI: 10.3389/fsurg.2022.917458. View

3.
Johnson A, Cipolla M . Altered hippocampal arteriole structure and function in a rat model of preeclampsia: Potential role in impaired seizure-induced hyperemia. J Cereb Blood Flow Metab. 2016; 37(8):2857-2869. PMC: 5536792. DOI: 10.1177/0271678X16676287. View

4.
Wakabayashi I, Sotoda Y, Hirooka S, Orita H . Association between cardiometabolic index and atherosclerotic progression in patients with peripheral arterial disease. Clin Chim Acta. 2015; 446:231-6. DOI: 10.1016/j.cca.2015.04.020. View

5.
Han L, Liu X, Li H, Zou J, Yang Z, Han J . Blood coagulation parameters and platelet indices: changes in normal and preeclamptic pregnancies and predictive values for preeclampsia. PLoS One. 2014; 9(12):e114488. PMC: 4252147. DOI: 10.1371/journal.pone.0114488. View