Epidemiology and Early Screening Strategies for Colorectal Cancer in China

Overview

Journal Chin J Cancer Res

Specialty Oncology

Date 2024 Jan 11

PMID 38204448

Authors

Yong Yang

Zhaoya Gao

An Huang

Jingyi Shi

Zhuang Sun

Haopeng Hong

Jin Gu

Affiliations

Soon will be listed here.

Abstract

China ranks the first worldwide in the number of new colorectal cancer (CRC) cases and CRC-related deaths. The increasing incidence of early-onset CRC in recent years highlights the challenges related to CRC screening and prevention. High-quality colonoscopy is the universally used gold standard for CRC screening. Risk assessment combined with a two-step screening strategy based on colonoscopy and non-invasive examinations was proven to be highly effective. However, systematic use of well-established risk factors associated with CRC, beyond age, could better identify those who might harbor advanced colorectal neoplasia, improve the diagnostic yield of current screening modalities, and optimize the selection of individuals who might benefit most from preventive strategies. "Personalization" and "Standardization" are the future development directions of CRC screening, from the initiation of screening in those at high risk for CRC to follow-up after treatment, which are the key to ensure the screening efficiency.

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