Non-Coding RNAs As Key Regulators in Lung Cancer

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2024 Jan 11

PMID 38203731

Authors

Irina Gilyazova

Galiya Gimalova

Aigul Nizamova

Elmira Galimova

Ekaterina Ishbulatova

Valentin Pavlov

Elza Khusnutdinova

Affiliations

Soon will be listed here.

Abstract

For several decades, most lung cancer investigations have focused on the search for mutations in candidate genes; however, in the last decade, due to the fact that most of the human genome is occupied by sequences that do not code for proteins, much attention has been paid to non-coding RNAs (ncRNAs) that perform regulatory functions. In this review, we principally focused on recent studies of the function, regulatory mechanisms, and therapeutic potential of ncRNAs including microRNA (miRNA), long ncRNA (lncRNA), and circular RNA (circRNA) in different types of lung cancer.

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