The Role of the Gut Microbiota in Anorexia Nervosa in Children and Adults-Systematic Review

Overview

Journal Int J Mol Sci

Publisher MDPI

Specialties Biochemistry
Chemistry
Molecular Biology

Date 2024 Jan 11

PMID 38203211

Authors

Dana-Teodora Anton-Paduraru

Felicia Trofin

Eduard Vasile Nastase

Radu Stefan Miftode

Ionela-Larisa Miftode

Mioara Florentina Trandafirescu

Elena Cojocaru

Elena Tarca

Dana Elena Mindru

Olivia Simona Dorneanu

Affiliations

Soon will be listed here.

Abstract

Among the factors incriminated in the appearance of eating disorders, intestinal microbiota has recently been implicated. Now there is evidence that the composition of gut microbiota is different in anorexia nervosa. We gathered many surveys on the changes in the profile of gut microbiota in patients with anorexia nervosa. This review comprehensively examines the contemporary experimental evidence concerning the bidirectional communication between gut microbiota and the brain. Drawing from recent breakthroughs in this area of research, we propose that the gut microbiota significantly contributes to the intricate interplay between the body and the brain, thereby contributing to overall healthy homeostasis while concurrently impacting disease risk, including anxiety and mood disorders. Particular attention is devoted to elucidating the structure and functional relevance of the gut microbiota in the context of Anorexia Nervosa.

Citing Articles

Gut-Brain Axis and Brain Microbiome Interactions from a Medical Perspective.

Arneth B Brain Sci. 2025; 15(2).

PMID: 40002500 PMC: 11853140. DOI: 10.3390/brainsci15020167.

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