Acute Kidney Injury and Hepatorenal Syndrome in Patients with Cirrhosis

Overview

Journal J Clin Med

Specialty General Medicine

Date 2024 Jan 11

PMID 38202206

Authors

Nazli Begum Ozturk

Ece Janet Dinc

Abhishek Swami

Ahmet Gurakar

Affiliations

Soon will be listed here.

Abstract

Acute kidney injury (AKI) is common in hospitalized patients with cirrhosis. Hepatorenal syndrome (HRS) is a type of AKI known as HRS-AKI. It is a severe complication of cirrhosis with high morbidity and mortality. While certain vasoconstrictor medications have been shown to improve HRS-AKI, no clear transplant-free survival benefit has been reported with medical therapies. Patients with HRS-AKI should be considered for urgent liver transplantation evaluation. In this review, we discuss the most recent updates on the definition, diagnosis, and management of AKI in cirrhosis, with special a emphasis on HRS.

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