Biomimetic Materials Based on Poly-3-hydroxybutyrate and Chlorophyll Derivatives

Overview

Journal Polymers (Basel)

Publisher MDPI

Date 2024 Jan 11

PMID 38201766

Authors

Polina M Tyubaeva

Kristina G Gasparyan

Roman R Romanov

Evgeny A Kolesnikov

Levon Y Martirosyan

Ekaterina A Larkina

Mikhail A Tyubaev

Affiliations

Soon will be listed here.

Abstract

Electrospinning of biomimetic materials is of particular interest due to the possibility of producing flexible layers with highly developed surfaces from a wide range of polymers. Additionally, electrospinning is characterized by a high simplicity of implementation and the ability to modify the produced fibrous materials, which resemble structures found in living organisms. This study explores new electrospun materials based on polyhydroxyalkanoates, specifically poly-3-hydroxybutyrate, modified with chlorophyll derivatives. The research investigates the impact of chlorophyll derivatives on the morphology, supramolecular structure, and key properties of nonwoven materials. The obtained results are of interest for the development of new flexible materials with low concentrations of chlorophyll derivatives.

Citing Articles

Electrospinning of Poly-3-Hydroxybutyrate Fibers Loaded with Chlorophyll for Antibacterial Purposes.

Tyubaeva P, Varyan I, Romanov R, Merzlikin V, Gruznova O, Gruznov D Polymers (Basel). 2024; 16(22).

PMID: 39599313 PMC: 11598136. DOI: 10.3390/polym16223221.

References

Pucci C, Martinelli C, DeglInnocenti A, Desii A, De Pasquale D, Ciofani G . Light-Activated Biomedical Applications of Chlorophyll Derivatives. Macromol Biosci. 2021; 21(9):e2100181. DOI: 10.1002/mabi.202100181. View

Woods I, Flanagan T . Electrospinning of biomimetic scaffolds for tissue-engineered vascular grafts: threading the path. Expert Rev Cardiovasc Ther. 2014; 12(7):815-32. DOI: 10.1586/14779072.2014.925397. View

He P, Yang G, Zhu D, Kong H, Corrales-Urena Y, Ciacchi L . Biomolecule-mimetic nanomaterials for photothermal and photodynamic therapy of cancers: Bridging nanobiotechnology and biomedicine. J Nanobiotechnology. 2022; 20(1):483. PMC: 9670580. DOI: 10.1186/s12951-022-01691-4. View

Carter G, Spiering B . Optical properties of intact leaves for estimating chlorophyll concentration. J Environ Qual. 2002; 31(5):1424-32. DOI: 10.2134/jeq2002.1424. View

Peng Q, Moan J, Nesland J . Correlation of subcellular and intratumoral photosensitizer localization with ultrastructural features after photodynamic therapy. Ultrastruct Pathol. 1996; 20(2):109-129. DOI: 10.3109/01913129609016306. View

Avossa J, Paolesse R, Di Natale C, Zampetti E, Bertoni G, De Cesare F . Electrospinning of Polystyrene/Polyhydroxybutyrate Nanofibers Doped with Porphyrin and Graphene for Chemiresistor Gas Sensors. Nanomaterials (Basel). 2019; 9(2). PMC: 6409903. DOI: 10.3390/nano9020280. View

Thanasekaran P, Chu C, Wang S, Chen K, Gao H, Lee M . Lipid-Wrapped Upconversion Nanoconstruct/Photosensitizer Complex for Near-Infrared Light-Mediated Photodynamic Therapy. ACS Appl Mater Interfaces. 2018; 11(1):84-95. DOI: 10.1021/acsami.8b07760. View

Zou Q, Bao J, Yan X . Functional Nanomaterials Based on Self-Assembly of Endogenic NIR-Absorbing Pigments for Diagnostic and Therapeutic Applications. Small Methods. 2022; 6(4):e2101359. DOI: 10.1002/smtd.202101359. View

Mollaeva M, Nikolskaya E, Beganovskaya V, Sokol M, Chirkina M, Obydennyi S . Oxidative Damage Induced by Phototoxic Pheophorbide a 17-Diethylene Glycol Ester Encapsulated in PLGA Nanoparticles. Antioxidants (Basel). 2021; 10(12). PMC: 8750000. DOI: 10.3390/antiox10121985. View

10.

Borisova I, Stoilova O, Manolova N, Rashkov I . Modulating the Mechanical Properties of Electrospun PHB/PCL Materials by Using Different Types of Collectors and Heat Sealing. Polymers (Basel). 2020; 12(3). PMC: 7183258. DOI: 10.3390/polym12030693. View

11.

Tyubaeva P, Varyan I, Lobanov A, Olkhov A, Popov A . Effect of the Hemin Molecular Complexes on the Structure and Properties of the Composite Electrospun Materials Based on Poly(3-hydroxybutyrate). Polymers (Basel). 2021; 13(22). PMC: 8622405. DOI: 10.3390/polym13224024. View

12.

Vieira Ferreira L, Machado I, Gama A, Socoteanu R, Boscencu R, Manda G . Photochemical /Photocytotoxicity Studies of New Tetrapyrrolic Structures as Potential Candidates for Cancer Theranostics. Curr Drug Discov Technol. 2019; 17(5):661-669. DOI: 10.2174/1570163816666190411100919. View

13.

McAdam B, Fournet M, McDonald P, Mojicevic M . Production of Polyhydroxybutyrate (PHB) and Factors Impacting Its Chemical and Mechanical Characteristics. Polymers (Basel). 2020; 12(12). PMC: 7761907. DOI: 10.3390/polym12122908. View

14.

Kumar A, Schweizer H . Bacterial resistance to antibiotics: active efflux and reduced uptake. Adv Drug Deliv Rev. 2005; 57(10):1486-513. DOI: 10.1016/j.addr.2005.04.004. View

15.

Lin B, Xu X, Zhang X, Yu Y, Wang X . Photodynamic Treatment of Colorectal Cancer Using Chlorin e6-Loaded Poly(lactide-co-glycolide)- Based Nanoparticles. J Biomed Nanotechnol. 2021; 17(10):1939-1950. DOI: 10.1166/jbn.2021.3170. View

16.

Imran M, Ramzan M, Qureshi A, Khan M, Tariq M . Emerging Applications of Porphyrins and Metalloporphyrins in Biomedicine and Diagnostic Magnetic Resonance Imaging. Biosensors (Basel). 2018; 8(4). PMC: 6316340. DOI: 10.3390/bios8040095. View

17.

Chu M, Li H, Wu Q, Wo F, Shi D . Pluronic-encapsulated natural chlorophyll nanocomposites for in vivo cancer imaging and photothermal/photodynamic therapies. Biomaterials. 2014; 35(29):8357-73. DOI: 10.1016/j.biomaterials.2014.05.049. View

18.

Lim L, Mendes A, Chronakis I . Electrospinning and electrospraying technologies for food applications. Adv Food Nutr Res. 2019; 88:167-234. DOI: 10.1016/bs.afnr.2019.02.005. View

19.

Dhilip Kumar S, Abrahamse H . Biocompatible Nanocarriers for Enhanced Cancer Photodynamic Therapy Applications. Pharmaceutics. 2021; 13(11). PMC: 8624654. DOI: 10.3390/pharmaceutics13111933. View

20.

Gerola A, Santana A, Franca P, Tsubone T, De Oliveira H, Caetano W . Effects of metal and the phytyl chain on chlorophyll derivatives: physicochemical evaluation for photodynamic inactivation of microorganisms. Photochem Photobiol. 2011; 87(4):884-94. DOI: 10.1111/j.1751-1097.2011.00935.x. View