Fluorescent Probes Based on Ag NPs@N/GQDs and Molecularly Imprinted Polymer for Sensitive Detection of Noradrenaline in Bananas

Overview

Journal J Fluoresc

Specialties Biophysics
Chemistry

Date 2024 Jan 9

PMID 38193952

Authors

Yaru Wang

Shuhuai Li

Xionghui Ma

Chaohai Pang

Yuwei Wu

Mingyue Wang

Bei Li

Sixin Liu

Affiliations

Soon will be listed here.

Abstract

Fluorescence intensity and selective recognition ability are crucial factors in determining the analytical techniques for fluorescent probes. In this study, a core-shell fluorescent material, composed of silver nanoparticles@nitrogen-doped graphene quantum dots (Ag NPs@N/GQDs), was synthesised using mango leaves as the raw material through a thermal cracking method, resulting in strong fluorescence luminescence intensity. By employing noradrenaline as a template molecule and using a surface molecular imprinting technique, a molecularly imprinted membrane (MIP) was formed on the surface of the fluorescent material, that was subsequently eluted to obtain a highly specific, fluorescent probe capable of recognising noradrenaline. The probe captured various concentrations of noradrenaline using the MIP, which decreased the fluorescence intensity. Then a method for detecting trace amounts of noradrenaline was established. This method exhibited a linear range from 0.5 -700 pM with a detection limit of 0.154 pM. The proposed method was implemented in banana samples. Satisfactory recoveries were confirmed at four different concentrations. The method presented a relative standard deviation (RSD) of less than 5.0%.

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PMID: 39685917 PMC: 11641839. DOI: 10.3390/jcm13237458.

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