A Rare Goblet Cell Adenocarcinoma Arising from Barrett's Esophagus: the First Reported Case in the Esophagus

Overview

Journal J Pathol Transl Med

Specialty Biomedical Engineering

Date 2024 Jan 5

PMID 38178706

Authors

Chi Eun Oh

Sung Eun Kim

Sun-Ju Oh

Affiliations

Soon will be listed here.

Abstract

Goblet cell adenocarcinoma (GCA) is a rare and distinctive amphicrine tumor comprised of goblet-like mucinous cells and neuroendocrine cells. It is believed to originate from pluripotent stem cells located at the base of crypts. GCA predominantly arises from the appendix, with a few reported cases in extra-appendiceal locations such as the colorectum, small intestine, and stomach. In this case report, we present a unique instance of a 64-year-old male who initially received a diagnosis of neuroendocrine carcinoma in the distal esophagus based on biopsy but, following resection, was subsequently re-diagnosed with GCA arising from Barrett's esophagus.

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