[Relationship Between Bacteria in the Lower Respiratory Tract/Lung Cancer  and the Development of Lung Cancer As Well As Its Clinical Application]

Overview

Journal Zhongguo Fei Ai Za Zhi

Specialties Oncology
Pulmonary Medicine

Date 2024 Jan 2

PMID 38163981

Authors

Bowen Li

Zhicheng Huang

Yadong Wang

Jianchao Xue

Yankai Xia

Yuan Xu

Huaxia Yang

Naixin Liang

Shanqing Li

Affiliations

Soon will be listed here.

Abstract

Due to the advancement of 16S rRNA sequencing technology, the lower respiratory tract microbiota, which was considered non-existent, has been revealed. The correlation between these microorganisms and diseases such as tumor has been a hot topic in recent years. As the bacteria in the surrounding can infiltrate the tumors, researchers have also begun to pay attention to the biological behavior of tumor bacteria and their interaction with tumors. In this review, we present the characteristic of the lower respiratory tract bacteria and summarize recent research findings on the relationship between these microbiota and lung cancer. On top of that, we also summarize the basic feature of bacteria in tumors and focus on the characteristic of the bacteria in lung cancer. The relationship between bacteria in lung cancer and tumor development is also been discussed. Finally, we review the potential clinical applications of bacterial communities in the lower respiratory tract and lung cancer, and summarize key points of sample collection, sequencing, and contamination control, hoping to provide new ideas for the screening and treatment of tumors. .

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[Relationship Between Bacteria in the Lower Respiratory Tract/Lung Cancer and the Development of Lung Cancer As Well As Its Clinical Application]

[Relationship Between Bacteria in the Lower Respiratory Tract/Lung Cancer  and the Development of Lung Cancer As Well As Its Clinical Application]