Lung Ultrasound Elastography by SWE2D and "Fibrosis-like" Computed Tomography Signs After COVID-19 Pneumonia: A Follow-Up Study

Overview

Journal J Clin Med

Specialty General Medicine

Date 2023 Dec 23

PMID 38137584

Authors

Carlos Paredes-Manjarrez

Francisco J Avelar-Garnica

Andres Tlacaelel Balderas-Chairez

Jorge Arellano-Sotelo

Ricardo Cordova-Ramirez

Eliseo Espinosa-Poblano

Alejandro Gonzalez-Ruiz

Juan Carlos Anda-Garay

Jose Adan Miguel-Puga

Kathrine Jauregui-Renaud

Affiliations

Soon will be listed here.

Abstract

The aim of this study was to assess the shear wave velocity by LUS elastography (SWE2D) for the evaluation of superficial lung stiffness after COVID-19 pneumonia, according to "fibrosis-like" signs found by Computed Tomography (CT), considering the respiratory function. Seventy-nine adults participated in the study 42 to 353 days from symptom onset. Paired evaluations (SWE2D and CT) were performed along with the assessment of arterial blood gases and spirometry, three times with 100 days in between. During the follow-up and within each evaluation, the SWE2D velocity changed over time (MANOVA, < 0.05) according to the extent of "fibrosis-like" CT signs by lung lobe (ANOVA, < 0.05). The variability of the SWE2D velocity was consistently related to the first-second forced expiratory volume and the forced vital capacity (MANCOVA, < 0.05), which changed over time with no change in blood gases. Covariance was also observed with age and patients' body mass index, the time from symptom onset until hospital admission, and the history of diabetes in those who required intensive care during the acute phase (MANCOVA, < 0.05). After COVID-19 pneumonia, SWE2D velocity can be related to the extent and regression of "fibrotic-like" involvement of the lung lobes, and it could be a complementary tool in the follow-up after COVID-19 pneumonia.

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