Superparamagnetic Artificial Cells PLGA-FeO Micro/Nanocapsules for Cancer Targeted Delivery

Overview

Journal Cancers (Basel)

Publisher MDPI

Specialty Oncology

Date 2023 Dec 23

PMID 38136352

Authors

Tao Wang

Thomas Ming Swi Chang

Affiliations

Soon will be listed here.

Abstract

Artificial cells have been extensively used in many fields, such as nanomedicine, biotherapy, blood substitutes, drug delivery, enzyme/gene therapy, cancer therapy, and the COVID-19 vaccine. The unique properties of superparamagnetic FeO nanoparticles have contributed to increased interest in using superparamagnetic artificial cells (PLGA-FeO micro/nanocapsules) for targeted therapy. In this review, the preparation methods of FeO NPs and superparamagnetic artificial cell PLGA-drug-FeO micro/nanocapsules are discussed. This review also focuses on the recent progress of superparamagnetic PLGA-drug-FeO micro/nanocapsules as targeted therapeutics. We shall concentrate on the use of superparamagnetic artificial cells in the form of PLGA-drug-FeO nanocapsules for magnetic hyperthermia/photothermal therapy and cancer therapies, including lung breast cancer and glioblastoma.

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