Vancomycin-resistant in Japan, 2007-2015: a Molecular Epidemiology Analysis Focused on Examining Strain Characteristics over Time

Overview

Journal Microbiol Spectr

Specialty Microbiology

Date 2023 Dec 15

PMID 38100166

Authors

Mieko Tokano

Norihito Tarumoto

Jun Sakai

Kazuo Imai

Masahiro Kodana

Toru Kawamura

Takuya Maeda

Shigefumi Maesaki

Affiliations

Soon will be listed here.

Abstract

Our study emphasizes the efficacy of whole-genome sequencing (WGS) in addressing outbreaks of vancomycin-resistant enterococci. WGS enables the identification and tracking of resistant bacterial strains, early detection and management of novel infectious disease outbreaks, and the appropriate selection and use of antibiotics. Furthermore, our approach deepens our understanding of how resistant bacteria transfer genes and adapt to their environments or hosts. For modern medicine, these insights have significant implications for controlling infections and effectively managing antibiotic use in the current era, where antibiotic resistance is progressing.

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