Harnessing the Power of Nutritional Antioxidants Against Adrenal Hormone Imbalance-associated Oxidative Stress

Overview

Journal Front Endocrinol (Lausanne)

Specialty Endocrinology

Date 2023 Dec 15

PMID 38098868

Authors

Anil Patani

Deepak Balram

Virendra Kumar Yadav

Kuang-Yow Lian

Ashish Patel

Dipak Kumar Sahoo

Affiliations

Soon will be listed here.

Abstract

Oxidative stress, resulting from dysregulation in the secretion of adrenal hormones, represents a major concern in human health. The present review comprehensively examines various categories of endocrine dysregulation within the adrenal glands, encompassing glucocorticoids, mineralocorticoids, and androgens. Additionally, a comprehensive account of adrenal hormone disorders, including adrenal insufficiency, Cushing's syndrome, and adrenal tumors, is presented, with particular emphasis on their intricate association with oxidative stress. The review also delves into an examination of various nutritional antioxidants, namely vitamin C, vitamin E, carotenoids, selenium, zinc, polyphenols, coenzyme Q10, and probiotics, and elucidates their role in mitigating the adverse effects of oxidative stress arising from imbalances in adrenal hormone levels. In conclusion, harnessing the power of nutritional antioxidants has the potential to help with oxidative stress caused by an imbalance in adrenal hormones. This could lead to new research and therapeutic interventions.

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