Percutaneous Gastrostomies in Advanced Cancer

Overview

Journal Porto Biomed J

Publisher Wolters Kluwer

Specialty Biomedical Engineering

Date 2023 Dec 14

PMID 38093796

Authors

Jose Antonio Ferraz-Goncalves

Susana Amaral

Filipa Pereira

Ligia Rodrigues Santos

Jose Guilherme Assis

Sergio Alves

Diana Martins

Affiliations

Soon will be listed here.

Abstract

Introduction: Gastrostomies can be performed percutaneously by interventional radiology (PRG) or endoscopy (PEG).

Methods: Retrospective analysis of patients with advanced cancer who underwent a gastrostomy in 2017 in an oncology center.

Results: In 2017, 164 patients underwent gastrostomies, and 137 (84%) were male. The median age was 60 years (range: 38-91). The predominant Eastern Cooperative Oncology Group (ECOG) performance status stage was 1, with 73 (45%) patients. Head and neck cancer was the most common diagnosis, with 127 (77%) cases. The most frequent reason for performing a gastrostomy was dysphagia, 132 (81%). Most gastrostomies were PEG, 121 (74%), followed by PRG, 41 (25%), and surgery, 2 (1%). Early complications occurred in 86 (52%) patients, and the most frequent of them were local pain in 69 (80%) patients and minor local bleeding in 13 (15%). Late complications occurred in 90 (55%) patients, and the most frequent was also local pain in 57 (63%) patients, followed by local infection in 8 (9%), tube extrusion in 7 (8%), and stomal leakage in 7 (8%). In the multivariable analysis, the factors associated with survival were lymph node metastases and the ECOG performance status. Until June 30th, 2022, 123 (75%) patients had died, and 41 (25%) were still alive.

Conclusion: Gastrostomies were performed predominantly in ECOG performance stage 1 patients with head and neck cancer and symptoms of dysphagia, and PEG was the most common procedure.

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