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Ultra-fast Whole-body Bone Tomoscintigraphies Achieved with a High-sensitivity 360° CZT Camera and a Dedicated Deep-learning Noise Reduction Algorithm

Overview
Journal Eur J Nucl Med Mol Imaging
Specialties Biophysics
Nuclear Medicine
Radiology
Date 2023 Dec 11
PMID 38082197
Authors
Achraf Bahloul
Antoine Verger
Yechiel Lamash
Nathaniel Roth
Diawad Dari
Pierre-Yves Marie
Laetitia Imbert
Affiliations
Soon will be listed here.
Abstract

Methods: DLNR was applied on whole-body images recorded after the injection of 545 ± 33 MBq of [Tc]Tc-HDP in 19 patients (14 with bone metastasis) and reconstructed with 100%, 90%, 80%, 70%, 60%, 50%, 40%, and 30% of the original SPECT recording times.

Results: Irrespective of recording time, DLNR enhanced the contrast-to-noise ratios and slightly decreased the standardized uptake values of bone lesions. Except in one markedly obese patient, the quality of DLNR processed images remained good-to-excellent down to 60% of the recording time, corresponding to around 6 min SPECT-recording.

Conclusion: Ultra-fast SPECT recordings of 6 min can be achieved when DLNR is applied on whole-body bone 360° CZT-SPECT.

Citing Articles

Standardized uptake value-based analysis of two-phase whole-body bone tomoscintigraphies recorded with a high-speed 360° CZT camera in patients with known or suspected inflammatory arthritis.

Rajadhas F, Imbert L, Fiorino M, Morizot C, Boucher V, Lamiral Z Eur J Nucl Med Mol Imaging. 2025; .

PMID: 39969541 DOI: 10.1007/s00259-025-07150-0.

Clinical performance of deep learning-enhanced ultrafast whole-body scintigraphy in patients with suspected malignancy.

Qi N, Pan B, Meng Q, Yang Y, Ding J, Yuan Z BMC Med Imaging. 2024; 24(1):236.

PMID: 39251959 PMC: 11385493. DOI: 10.1186/s12880-024-01422-1.

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