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New Research Frontiers Pertaining to the Infant Gut Microbiota

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Date 2023 Dec 4
PMID 38046907
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Abstract

The human gut microbiota is believed to be responsible for multiple health-impacting host effects. The influence of gut microorganisms on the human host begins immediately after birth, having long-lasting health effects, while the gut microbiota itself continues to develop throughout the host's entire life. The purported health-associated effects of the gut microbiota have fueled extensive and ongoing research efforts. Nonetheless, the precise mode of action of functionalities exerted by microbial colonizers of the infant intestine is still largely unknown. The current perspective intends to illustrate major future investigative directions concerning the human gut microbiota with a specific focus on infant-associated gut microbes.

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References
1.
Milani C, Mancabelli L, Lugli G, Duranti S, Turroni F, Ferrario C . Exploring Vertical Transmission of Bifidobacteria from Mother to Child. Appl Environ Microbiol. 2015; 81(20):7078-87. PMC: 4579462. DOI: 10.1128/AEM.02037-15. View

2.
Eggesbo M, Botten G, Stigum H, Nafstad P, Magnus P . Is delivery by cesarean section a risk factor for food allergy?. J Allergy Clin Immunol. 2003; 112(2):420-6. DOI: 10.1067/mai.2003.1610. View

3.
Nguyen T, Vieira-Silva S, Liston A, Raes J . How informative is the mouse for human gut microbiota research?. Dis Model Mech. 2015; 8(1):1-16. PMC: 4283646. DOI: 10.1242/dmm.017400. View

4.
Yassour M, Jason E, Hogstrom L, Arthur T, Tripathi S, Siljander H . Strain-Level Analysis of Mother-to-Child Bacterial Transmission during the First Few Months of Life. Cell Host Microbe. 2018; 24(1):146-154.e4. PMC: 6091882. DOI: 10.1016/j.chom.2018.06.007. View

5.
Milani C, Duranti S, Bottacini F, Casey E, Turroni F, Mahony J . The First Microbial Colonizers of the Human Gut: Composition, Activities, and Health Implications of the Infant Gut Microbiota. Microbiol Mol Biol Rev. 2017; 81(4). PMC: 5706746. DOI: 10.1128/MMBR.00036-17. View