Population Dynamics and Insecticide Resistance in (Lepidoptera: Gelechiidae), an Invasive Pest on Tomato in Kenya

Overview

Journal Heliyon

Specialty Social Sciences

Date 2023 Nov 29

PMID 38027621

Authors

Maureen Adhiambo Ongonge

Inusa Jacob Ajene

Steven Runo

Bonoukpoe Mawuko Sokame

Fathiya Mbarak Khamis

Affiliations

Soon will be listed here.

Abstract

feeds on solanaceous plants with preference on tomato. Management of the pest is mostly with chemical insecticides. This study identified insecticide resistant populations and predicted resistance to insecticides. Insecticide resistance development was modelled using system thinking, and system dynamics approaches. The model showed the pest resistance development is alarming with an exponential increase of the resistance strength mostly in recent years. Furthermore, we used seven insecticide-resistance gene markers to resolve the population structure and genetic differentiation of insecticide-resistant populations in Kenya. The genes for resistance (knockdown resistance () mutations, acetylcholinesterase (AChE) and voltage gated sodium channel (para)) were detected in all populations. Population structure analyses separated populations into three genetic clusters with resistant genes that are interconnected. A better insight on the population dynamics and the genetic structure resistant genes in Kenya will help estimate resistance strength and determine the most effective pest control strategies.

References

Van Leeuwen T, Dermauw W, Mavridis K, Vontas J . Significance and interpretation of molecular diagnostics for insecticide resistance management of agricultural pests. Curr Opin Insect Sci. 2020; 39:69-76. DOI: 10.1016/j.cois.2020.03.006. View

Zhang C, Wu L, Luo C, Guo X, Yang R, Zhang Y . Population genetic structure and evolutionary genetics of Anopheles sinensis based on knockdown resistance (kdr) mutations and mtDNA-COII gene in China-Laos, Thailand-Laos, and Cambodia-Laos borders. Parasit Vectors. 2022; 15(1):229. PMC: 9233850. DOI: 10.1186/s13071-022-05366-9. View

Ajene I, Khamis F, van Asch B, Pietersen G, Seid N, Rwomushana I . Distribution of Candidatus Liberibacter species in Eastern Africa, and the First Report of Candidatus Liberibacter asiaticus in Kenya. Sci Rep. 2020; 10(1):3919. PMC: 7054587. DOI: 10.1038/s41598-020-60712-0. View

Li Y, Liu J . StructureSelector: A web-based software to select and visualize the optimal number of clusters using multiple methods. Mol Ecol Resour. 2017; 18(1):176-177. DOI: 10.1111/1755-0998.12719. View

Kamvar Z, Tabima J, Grunwald N . Poppr: an R package for genetic analysis of populations with clonal, partially clonal, and/or sexual reproduction. PeerJ. 2014; 2:e281. PMC: 3961149. DOI: 10.7717/peerj.281. View

Sandeu M, Mulamba C, Weedall G, Wondji C . A differential expression of pyrethroid resistance genes in the malaria vector Anopheles funestus across Uganda is associated with patterns of gene flow. PLoS One. 2020; 15(11):e0240743. PMC: 7654797. DOI: 10.1371/journal.pone.0240743. View

Fournier D . Mutations of acetylcholinesterase which confer insecticide resistance in insect populations. Chem Biol Interact. 2005; 157-158:257-61. DOI: 10.1016/j.cbi.2005.10.040. View

Hemingway J, Hawkes N, McCarroll L, Ranson H . The molecular basis of insecticide resistance in mosquitoes. Insect Biochem Mol Biol. 2004; 34(7):653-65. DOI: 10.1016/j.ibmb.2004.03.018. View

Jombart T . adegenet: a R package for the multivariate analysis of genetic markers. Bioinformatics. 2008; 24(11):1403-5. DOI: 10.1093/bioinformatics/btn129. View

10.

Weill M, Fort P, Berthomieu A, Dubois M, Pasteur N, Raymond M . A novel acetylcholinesterase gene in mosquitoes codes for the insecticide target and is non-homologous to the ace gene in Drosophila. Proc Biol Sci. 2002; 269(1504):2007-16. PMC: 1691131. DOI: 10.1098/rspb.2002.2122. View

11.

LINDQUIST A, WILSON H . Development of a Strain of Houseflies Resistant to DDT. Science. 1948; 107(2776):276. DOI: 10.1126/science.107.2776.276. View

12.

Roditakis E, Steinbach D, Moritz G, Vasakis E, Stavrakaki M, Ilias A . Ryanodine receptor point mutations confer diamide insecticide resistance in tomato leafminer, Tuta absoluta (Lepidoptera: Gelechiidae). Insect Biochem Mol Biol. 2016; 80:11-20. DOI: 10.1016/j.ibmb.2016.11.003. View

13.

Peakall R, Smouse P . GenAlEx 6.5: genetic analysis in Excel. Population genetic software for teaching and research--an update. Bioinformatics. 2012; 28(19):2537-9. PMC: 3463245. DOI: 10.1093/bioinformatics/bts460. View

14.

Silva J, Assis C, Ribeiro L, Siqueira H . Field-Evolved Resistance and Cross-Resistance of Brazilian Tuta absoluta (Lepidoptera: Gelechiidae) Populations to Diamide Insecticides. J Econ Entomol. 2016; 109(5):2190-2195. DOI: 10.1093/jee/tow161. View

15.

WILSON H, GAHAN J . Susceptibility of DDT-resistant Houseflies to Other Insecticidal Sprays. Science. 1948; 107(2776):276-7. DOI: 10.1126/science.107.2776.276-a. View

16.

Roditakis E, Mavridis K, Riga M, Vasakis E, Morou E, Rison J . Identification and detection of indoxacarb resistance mutations in the para sodium channel of the tomato leafminer, Tuta absoluta. Pest Manag Sci. 2016; 73(8):1679-1688. DOI: 10.1002/ps.4513. View

17.

McGraw E, ONeill S . Beyond insecticides: new thinking on an ancient problem. Nat Rev Microbiol. 2013; 11(3):181-93. DOI: 10.1038/nrmicro2968. View

18.

Ajene I, Khamis F, van Asch B, Pietersen G, Seid N, Wairimu A . Genetic diversity of (Hemiptera: Liviidae) unravels phylogeographic structure and invasion history of eastern African populations. Ecol Evol. 2022; 12(7):e9090. PMC: 9289372. DOI: 10.1002/ece3.9090. View

19.

Donnelly M, Corbel V, Weetman D, Wilding C, Williamson M, Black 4th W . Does kdr genotype predict insecticide-resistance phenotype in mosquitoes?. Trends Parasitol. 2009; 25(5):213-9. DOI: 10.1016/j.pt.2009.02.007. View

20.

Sokame B, Tonnang H, Subramanian S, Bruce A, Dubois T, Ekesi S . A system dynamics model for pests and natural enemies interactions. Sci Rep. 2021; 11(1):1401. PMC: 7809103. DOI: 10.1038/s41598-020-79553-y. View