Genetic Polymorphisms Involved in Bladder Cancer: A Global Review

Overview

Journal Oncol Rev

Specialty Oncology

Date 2023 Nov 29

PMID 38025894

Authors

Hampig Raphael Kourie

Joseph Zouein

Bahaa Succar

Avedis Mardirossian

Nizar Ahmadieh

Eliane Chouery

Cybel Mehawej

Nadine Jalkh

Joseph Kattan

Elie Nemr

Affiliations

Soon will be listed here.

Abstract

Bladder cancer (BC) has been associated with genetic susceptibility. Single peptide polymorphisms (SNPs) can modulate BC susceptibility. A literature search was performed covering the period between January 2000 and October 2020. Overall, 334 articles were selected, reporting 455 SNPs located in 244 genes. The selected 455 SNPs were further investigated. All SNPs that were associated with smoking and environmental exposure were excluded from this study. A total of 197 genes and 343 SNPs were found to be associated with BC, among which 177 genes and 291 SNPs had congruent results across all available studies. These genes and SNPs were classified into eight different categories according to their function.

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