Temperature Control in Sepsis

Overview

Journal Front Med (Lausanne)

Specialty General Medicine

Date 2023 Nov 29

PMID 38020082

Authors

Marc Doman

Michael Thy

Julien Dessajan

Mariem Dlela

Hermann Do Rego

Erwann Cariou

Michael Ejzenberg

Lila Bouadma

Etienne de Montmollin

Jean-Francois Timsit

Affiliations

Soon will be listed here.

Abstract

Fever can be viewed as an adaptive response to infection. Temperature control in sepsis is aimed at preventing potential harms associated with high temperature (tachycardia, vasodilation, electrolyte and water loss) and therapeutic hypothermia may be aimed at slowing metabolic activities and protecting organs from inflammation. Although high fever (>39.5°C) control is usually performed in critically ill patients, available cohorts and randomized controlled trials do not support its use to improve sepsis prognosis. Finally, both spontaneous and therapeutic hypothermia are associated with poor outcomes in sepsis.

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