A 12-Year Comparison of Alzheimer's Dementia Patients With Their Informants in Taiwan

Overview

Journal Am J Alzheimers Dis Other Demen

Publisher Sage Publications

Specialty Neurology

Date 2023 Nov 28

PMID 38016118

Authors

Kai-Ming Jhang

Wen-Fu Wang

Kuang-Nan Hsu

Shang-Chien Huang

Sheng-Hsiang Yang

Ling-Chun Huang

Yuan-Han Yang

Affiliations

Soon will be listed here.

Abstract

Background: To update the characteristics of patients with Alzheimer's disease (AD) and their informants in Taiwan and compare them from 12 years ago.

Methods: 1218 patients with AD and their informants were recruited from six hospitals in Taiwan. The uniform data set version 3.0 (UDS3, form A1-A3) were administered.

Results: Compared with the first registration from 2010-2012 (n = 691), the mean clinical dementia rating sum of boxes score was significantly lower, more patients living independently, and more informants not living together with the patients. A total of 11.2%, 4.1%, 12.8%, and 0.5% of the patients had a reported history of cognitive impairment in their mothers, fathers, siblings, and children, respectively.

Conclusion: Compared with the data from 2010, patients have been diagnosed at a milder disease stage, and their informants used telephone contact more frequently instead of living with the patients. Family histories of cognitive impairment in patients with AD remain frequent.

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