The Clinical Diagnosis of Alzheimer's Disease

Overview

Journal Arch Neurol

Specialty Neurology

Date 1987 Jan 1

PMID 3800717

Citations 33

Authors

J P Wade

T R Mirsen

V C Hachinski

M Fisman

C Lau

H Merskey

Affiliations

Soon will be listed here.

Abstract

Clinical and pathologic diagnoses are compared in 65 patients who had dementia and who had been studied longitudinally during life. The sensitivity of diagnosis for dementia of the Alzheimer type (DAT) without any other diagnosis was 87%, and the specificity was 78%. The ischemic scale score did not discriminate well between patients with pure multi-infarct dementia and those with both DAT and multi-infarct dementia. However, 35 of 38 cases of pure DAT had a score of 4 or less on the ischemic scale.

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