Skin-Related Sexual Life Questionnaire (SRSLQ): Creation and Validation of the Questionnaire

Overview

Journal Medicina (Kaunas)

Publisher MDPI

Specialty General Medicine

Date 2023 Nov 25

PMID 38004072

Authors

Kamila Kedra

Adam Reich

Affiliations

Soon will be listed here.

Abstract

: The assessment of sexual dysfunction among psoriatic patients still remains a great diagnostic difficulty due to its subjective and embarrassing character. Various questionnaires have been used to assess sexual dysfunctions associated with skin conditions; however, none of them have been approved as a gold standard. The aim of our study was to create and validate the Skin-Related Sexual Life Questionnaire (SRSLQ) for the assessment of possible sexual dysfunction and related psychological burdens in patients with skin diseases. : A total of 109 patients, including 45 women and 64 men (1:1.4) suffering from psoriasis and aged between 18 and 73 years (mean 48.0 ± 13.4 years), were included in the study. All subjects completed the 11-item SRSLQ and the Dermatology Life Quality Index (DLQI). In addition, all men were asked to fulfil the five-item version of the International Index of Erectile Dysfunction (IIEF-5) at the time of examination and 7 days after enrollment. The disease severity was assessed via the PASI scale. : The statistical analysis of internal consistency of SRSLQ showed very good integrity, with a Cronbach α coefficient of 0.94. The reproducibility level assessed with intraclass correlation coefficient (ICC) amounted to 0.96. A significant correlation between the total score of the 11-item SRSDQ and the DLQI (r = 0.39; < 0.001) was found, confirming congruent validity. : The validated 11-item Skin-Related Sexual Life Questionnaire can be successfully implemented in daily clinical practice as well as in clinical research.

References

Jaworecka K, Rzepko M, Marek-Jozefowicz L, Tamer F, Stefaniak A, Szczegielniak M . The Impact of Pruritus on the Quality of Life and Sleep Disturbances in Patients Suffering from Different Clinical Variants of Psoriasis. J Clin Med. 2022; 11(19). PMC: 9572740. DOI: 10.3390/jcm11195553. View

Sahi F, Masood A, Danawar N, Mekaiel A, Malik B . Association Between Psoriasis and Depression: A Traditional Review. Cureus. 2020; 12(8):e9708. PMC: 7489316. DOI: 10.7759/cureus.9708. View

Zhang H, Yang Z, Tang K, Sun Q, Jin H . Stigmatization in Patients With Psoriasis: A Mini Review. Front Immunol. 2021; 12:715839. PMC: 8634029. DOI: 10.3389/fimmu.2021.715839. View

Kurizky P, Martins G, Carneiro J, Gomes C, Mota L . Evaluation of the occurrence of sexual dysfunction and general quality of life in female patients with psoriasis. An Bras Dermatol. 2018; 93(6):801-806. PMC: 6256218. DOI: 10.1590/abd1806-4841.20183071. View

Shah S, Merchant S, Shah S . Female sexual dysfunction in psoriasis: a systematic review and meta-analysis using the Female Sexual Function Index. Int J Impot Res. 2022; 36(3):232-241. DOI: 10.1038/s41443-022-00650-9. View

Guenther L, Han C, Szapary P, Schenkel B, Poulin Y, Bourcier M . Impact of ustekinumab on health-related quality of life and sexual difficulties associated with psoriasis: results from two phase III clinical trials. J Eur Acad Dermatol Venereol. 2011; 25(7):851-7. DOI: 10.1111/j.1468-3083.2011.04082.x. View

Al-Mazeedi K, El-Shazly M, Al-Ajmi H . Impact of psoriasis on quality of life in Kuwait. Int J Dermatol. 2006; 45(4):418-24. DOI: 10.1111/j.1365-4632.2006.02502.x. View

Molina-Leyva A, Salvador-Rodriguez L, Martinez-Lopez A, Ruiz-Carrascosa J, Arias-Santiago S . Association Between Psoriasis and Sexual and Erectile Dysfunction in Epidemiologic Studies: A Systematic Review. JAMA Dermatol. 2018; 155(1):98-106. DOI: 10.1001/jamadermatol.2018.3442. View

Dong X, Zheng Y, Shi T, Liu H . Effects of tumor necrosis factor-alpha on sexual activity of male patients with ankylosing spondylitis. Clin Rheumatol. 2014; 34(5):915-20. DOI: 10.1007/s10067-014-2751-7. View

10.

Molina-Leyva A, Almodovar-Real A, Ruiz-Carrascosa J, Naranjo-Sintes R, Serrano-Ortega S, Jimenez-Moleon J . Distribution pattern of psoriasis affects sexual function in moderate to severe psoriasis: a prospective case series study. J Sex Med. 2014; 11(12):2882-9. DOI: 10.1111/jsm.12710. View

11.

Megna M, Camela E, Battista T, Genco L, Martora F, Noto M . Efficacy and safety of biologics and small molecules for psoriasis in pediatric and geriatric populations. Part II: focus on elderly patients. Expert Opin Drug Saf. 2023; 22(1):43-58. DOI: 10.1080/14740338.2023.2173171. View

12.

Wojciechowska-Zdrojowy M, Reid A, Szepietowski J, Wojciechowski A . Analysis of Sexual Problems in Men With Psoriasis. J Sex Marital Ther. 2018; 44(8):737-745. DOI: 10.1080/0092623X.2018.1462276. View

13.

Rhoden E, Teloken C, Sogari P, Vargas Souto C . The use of the simplified International Index of Erectile Function (IIEF-5) as a diagnostic tool to study the prevalence of erectile dysfunction. Int J Impot Res. 2002; 14(4):245-50. DOI: 10.1038/sj.ijir.3900859. View

14.

Rapp S, Feldman S, Exum M, Fleischer Jr A, Reboussin D . Psoriasis causes as much disability as other major medical diseases. J Am Acad Dermatol. 1999; 41(3 Pt 1):401-7. DOI: 10.1016/s0190-9622(99)70112-x. View

15.

Russo P, Ilchef R, Cooper A . Psychiatric morbidity in psoriasis: a review. Australas J Dermatol. 2004; 45(3):155-9. DOI: 10.1111/j.1440-0960.2004.00078.x. View

16.

Duarte G, Calmon H, Radel G, de Oliveira M . Psoriasis and sexual dysfunction: links, risks, and management challenges. Psoriasis (Auckl). 2018; 8:93-99. PMC: 6292237. DOI: 10.2147/PTT.S159916. View

17.

Meeuwis K, de Hullu J, van de Nieuwenhof H, Evers A, Massuger L, van de Kerkhof P . Quality of life and sexual health in patients with genital psoriasis. Br J Dermatol. 2011; 164(6):1247-55. DOI: 10.1111/j.1365-2133.2011.10249.x. View

18.

Hedemann T, Liu X, Kang C, Husain M . Associations between psoriasis and mental illness: an update for clinicians. Gen Hosp Psychiatry. 2022; 75:30-37. DOI: 10.1016/j.genhosppsych.2022.01.006. View

19.

Mateu-Arrom L, Puig L . Genetic and Epigenetic Mechanisms of Psoriasis. Genes (Basel). 2023; 14(8). PMC: 10454222. DOI: 10.3390/genes14081619. View

20.

Meeuwis K, Potts Bleakman A, van de Kerkhof P, Dutronc Y, Henneges C, Kornberg L . Prevalence of genital psoriasis in patients with psoriasis. J Dermatolog Treat. 2018; 29(8):754-760. DOI: 10.1080/09546634.2018.1453125. View