» Articles » PMID: 37998586

Evaluation of the Easy Albumin-Bilirubin Score As a Prognostic Tool for Mortality in Adult Trauma Patients in the Intensive Care Unit: A Retrospective Study

Overview
Specialty Radiology
Date 2023 Nov 24
PMID 37998586
Authors
Affiliations
Soon will be listed here.
Abstract

The easy albumin-bilirubin (EZ-ALBI) score is derived using the following equation: total bilirubin (mg/dL) - 9 × albumin (g/dL). This study aimed to determine whether the EZ-ALBI score predicted mortality risk in adult trauma patients in an intensive care unit (ICU). Data from a hospital's trauma database were retrospectively evaluated for 1083 adult trauma ICU patients (139 deaths and 944 survivors) between 1 January 2016 and 31 December 2021. Patients were classified based on the ideal EZ-ALBI cut-off of -26.5, which was determined via receiver operating characteristic curve analysis. The deceased patients' EZ-ALBI scores were higher than those of the surviving patients (-26.8 ± 6.5 vs. -30.3 ± 5.9, = 0.001). Multivariate logistic analysis revealed that, in addition to age, the presence of end-stage renal disease, Glasgow Coma Scale scores, and injury severity scores, the EZ-ALBI score is an independent risk factor for mortality (odds ratio (OR), 1.10; 95% confidence interval (CI): 1.06-1.14; = 0.001)). Compared with patients with EZ-ALBI scores < -26.5, those with scores ≥ -26.5 had a 2.1-fold higher adjusted mortality rate (adjusted OR, 2.14; 95% CI: 1.43-3.19, = 0.001). In conclusion, the EZ-ALBI score is a substantial and independent predictor of mortality and can be screened to stratify mortality risk in adult trauma ICU patients.

References
1.
Roberts I, Blackhall K, Alderson P, Bunn F, Schierhout G . Human albumin solution for resuscitation and volume expansion in critically ill patients. Cochrane Database Syst Rev. 2011; (11):CD001208. PMC: 7055200. DOI: 10.1002/14651858.CD001208.pub4. View

2.
Liao J, Ho S, Liu P, Hsu C, Huang Y, Su C . Prognostic Prediction for Patients with Hepatocellular Carcinoma and Ascites: Role of Albumin-Bilirubin (ALBI) Grade and Easy (EZ)-ALBI Grade. Cancers (Basel). 2023; 15(3). PMC: 9913159. DOI: 10.3390/cancers15030753. View

3.
Han S, Wang C, Tong F, Li Y, Li Z, Sun Z . Prognostic impact of albumin-bilirubin score on the prediction of in-hospital mortality in patients with heart failure: a retrospective cohort study. BMJ Open. 2022; 12(1):e049325. PMC: 8728421. DOI: 10.1136/bmjopen-2021-049325. View

4.
Chan A, Kumada T, Toyoda H, Tada T, Chong C, Mo F . Integration of albumin-bilirubin (ALBI) score into Barcelona Clinic Liver Cancer (BCLC) system for hepatocellular carcinoma. J Gastroenterol Hepatol. 2016; 31(7):1300-6. DOI: 10.1111/jgh.13291. View

5.
Su T, Yang H, Zhou Y, Huang Y, Liang P, Cheng T . Albumin - bilirubin (ALBI) versus Child-Turcotte-Pugh (CTP) in prognosis of HCC after stereotactic body radiation therapy. Radiat Oncol. 2019; 14(1):50. PMC: 6436219. DOI: 10.1186/s13014-019-1251-y. View