Surgical Treatment for Early Cervical Cancer in the HPV Era: State of the Art

Overview

Journal Healthcare (Basel)

Specialty Health Services

Date 2023 Nov 24

PMID 37998434

Authors

Mario Palumbo

Luigi Della Corte

Carlo Ronsini

Serena Guerra

Pierluigi Giampaolino

Giuseppe Bifulco

Affiliations

Soon will be listed here.

Abstract

Cervical cancer (CC) is the fourth most common cancer among women worldwide. The aim of this study is to focus on the state of the art of CC prevention, early diagnosis, and treatment and, within the latter, the role of surgery in the various stages of the disease with a focus on the impact of the LACC study (Laparoscopic Approach to Cervical Cancer trial) on the scientific debate and clinical practice. We have discussed the controversial application of minimally invasive surgery (MIS) for tumors < 2 cm and the possibility of fertility-sparing surgery on young women desirous of pregnancy. This analysis provides support for surgeons in the choice of better management, including patients with a desire for offspring and the need for sentinel node biopsy (SNB) rather than pelvic lymphadenectomy for tumors < 4 cm, and without suspicious lymph nodes' involvement on imaging. Vaccines and early diagnosis of pre-cancerous lesions are the most effective public health tool to tackle cervical cancer worldwide.

Citing Articles

Paric A, Tomic K, Alidzanovic L, Fojnica A, Vranic S Acta Med Acad. 2024; 53(3):237-273.

PMID: 39655353 PMC: 11831570. DOI: 10.5644/ama2006-124.458.

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