Nanomaterials-Based Biosensors for COVID-19 Detection-A Review

Overview

Journal IEEE Sens J

Date 2023 Nov 17

PMID 37974905

Authors

Sakshi Sharma

Sonakshi Saini

Maya Khangembam

Vinod Singh

Affiliations

Soon will be listed here.

Abstract

This review paper discusses the properties of nanomaterials, namely graphene, molybdenum disulfide, carbon nanotubes, and quantum dots for unique sensing applications. Based on the specific analyte to be detected and the functionalization techniques that are employed, some noteworthy sensors that have been developed are discussed. Further, biocompatible sensors fabricated from these materials capable of detecting specific chemical compounds are also highlighted for COVID-19 detection purposes, which can aid in efficient and reliable sensing as well as timely diagnosis.

Citing Articles

Emerging Trends of Gold Nanostructures for Point-of-Care Biosensor-Based Detection of COVID-19.

Yadav A, Basavegowda N, Shirin S, Raju S, Sekar R, Somu P Mol Biotechnol. 2024; .

PMID: 38703305 DOI: 10.1007/s12033-024-01157-y.

Advancement in COVID-19 detection using nanomaterial-based biosensors.

Truong P, Yin Y, Lee D, Ko S Exploration (Beijing). 2023; 3(1):20210232.

PMID: 37323622 PMC: 10191025. DOI: 10.1002/EXP.20210232.

Nano-based techniques: A revolutionary approach to prevent covid-19 and enhancing human awareness.

Annamalai A, Karuppaiya V, Ezhumalai D, Cheruparambath P, Balakrishnan K, Venkatesan A J Drug Deliv Sci Technol. 2023; 86:104567.

PMID: 37313114 PMC: 10183109. DOI: 10.1016/j.jddst.2023.104567.

Recent trends in carbon nanotube (CNT)-based biosensors for the fast and sensitive detection of human viruses: a critical review.

Meskher H, Mustansar H, Thakur A, Sathyamurthy R, Lynch I, Singh P Nanoscale Adv. 2023; 5(4):992-1010.

PMID: 36798507 PMC: 9926911. DOI: 10.1039/d2na00236a.

Handheld, Low-Cost, Aptamer-Based Sensing Device for Rapid SARS-CoV-2 RNA Detection Using Novelly Synthesized Gold Nanoparticles.

Kiruba Daniel S, Pai P, Sabbella H, Singh K, Rangaiah A, Basawarajappa S IEEE Sens J. 2022; 22(19):18437-18445.

PMID: 36416744 PMC: 9647715. DOI: 10.1109/JSEN.2022.3196598.

References

Qiu M, Shi Y, Guo Z, Chen Z, He R, Chen R . Antibody responses to individual proteins of SARS coronavirus and their neutralization activities. Microbes Infect. 2005; 7(5-6):882-9. PMC: 7110836. DOI: 10.1016/j.micinf.2005.02.006. View

Liu Q, Xu S, Niu C, Li M, He D, Lu Z . Distinguish cancer cells based on targeting turn-on fluorescence imaging by folate functionalized green emitting carbon dots. Biosens Bioelectron. 2014; 64:119-25. DOI: 10.1016/j.bios.2014.08.052. View

Mavrikou S, Moschopoulou G, Tsekouras V, Kintzios S . Development of a Portable, Ultra-Rapid and Ultra-Sensitive Cell-Based Biosensor for the Direct Detection of the SARS-CoV-2 S1 Spike Protein Antigen. Sensors (Basel). 2020; 20(11). PMC: 7309076. DOI: 10.3390/s20113121. View

Wang N, Wang Y, Guo T, Yang T, Chen M, Wang J . Green preparation of carbon dots with papaya as carbon source for effective fluorescent sensing of Iron (III) and Escherichia coli. Biosens Bioelectron. 2016; 85:68-75. DOI: 10.1016/j.bios.2016.04.089. View

Wu H, Wang J, Kang X, Wang C, Wang D, Liu J . Glucose biosensor based on immobilization of glucose oxidase in platinum nanoparticles/graphene/chitosan nanocomposite film. Talanta. 2009; 80(1):403-6. DOI: 10.1016/j.talanta.2009.06.054. View

Bae P, Kim K, Lee S, Chang H, Lee C, Park J . The modification of quantum dot probes used for the targeted imaging of his-tagged fusion proteins. Biomaterials. 2008; 30(5):836-42. DOI: 10.1016/j.biomaterials.2008.10.049. View

Michalet X, Pinaud F, Bentolila L, Tsay J, Doose S, Li J . Quantum dots for live cells, in vivo imaging, and diagnostics. Science. 2005; 307(5709):538-44. PMC: 1201471. DOI: 10.1126/science.1104274. View

Miripour Z, Sarrami-Forooshani R, Sanati H, Makarem J, Taheri M, Shojaeian F . Real-time diagnosis of reactive oxygen species (ROS) in fresh sputum by electrochemical tracing; correlation between COVID-19 and viral-induced ROS in lung/respiratory epithelium during this pandemic. Biosens Bioelectron. 2020; 165:112435. PMC: 7341050. DOI: 10.1016/j.bios.2020.112435. View

Resch-Genger U, Grabolle M, Cavaliere-Jaricot S, Nitschke R, Nann T . Quantum dots versus organic dyes as fluorescent labels. Nat Methods. 2008; 5(9):763-75. DOI: 10.1038/nmeth.1248. View

10.

Park Y, Walls A, Wang Z, Sauer M, Li W, Tortorici M . Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors. Nat Struct Mol Biol. 2019; 26(12):1151-1157. PMC: 7097669. DOI: 10.1038/s41594-019-0334-7. View

11.

Chang Y, Han H, Kim M . Analyzing the microstructure and related properties of 2D materials by transmission electron microscopy. Appl Microsc. 2021; 49(1):10. PMC: 7809582. DOI: 10.1186/s42649-019-0013-5. View

12.

Xu X, Yu C, Qu J, Zhang L, Jiang S, Huang D . Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2. Eur J Nucl Med Mol Imaging. 2020; 47(5):1275-1280. PMC: 7080117. DOI: 10.1007/s00259-020-04735-9. View

13.

Patir K, Gogoi S . Nitrogen-doped carbon dots as fluorescence ON-OFF-ON sensor for parallel detection of copper(ii) and mercury(ii) ions in solutions as well as in filter paper-based microfluidic device. Nanoscale Adv. 2022; 1(2):592-601. PMC: 9473229. DOI: 10.1039/c8na00080h. View

14.

Feldstein L, Rose E, Horwitz S, Collins J, Newhams M, Son M . Multisystem Inflammatory Syndrome in U.S. Children and Adolescents. N Engl J Med. 2020; 383(4):334-346. PMC: 7346765. DOI: 10.1056/NEJMoa2021680. View

15.

Levy M, Cater S, Ellington A . Quantum-dot aptamer beacons for the detection of proteins. Chembiochem. 2005; 6(12):2163-6. DOI: 10.1002/cbic.200500218. View

16.

Song Z, Huang Z, Liu J, Hu Z, Zhang J, Zhang G . Fully Stretchable and Humidity-Resistant Quantum Dot Gas Sensors. ACS Sens. 2018; 3(5):1048-1055. DOI: 10.1021/acssensors.8b00263. View

17.

Huang K, Liu Y, Liu Y, Wang L . Molybdenum disulfide nanoflower-chitosan-Au nanoparticles composites based electrochemical sensing platform for bisphenol A determination. J Hazard Mater. 2014; 276:207-15. DOI: 10.1016/j.jhazmat.2014.05.037. View

18.

Zhang W, Zhang P, Su Z, Wei G . Synthesis and sensor applications of MoS2-based nanocomposites. Nanoscale. 2015; 7(44):18364-78. DOI: 10.1039/c5nr06121k. View

19.

Chang E, Miller J, Sun J, Yu W, Colvin V, Drezek R . Protease-activated quantum dot probes. Biochem Biophys Res Commun. 2005; 334(4):1317-21. DOI: 10.1016/j.bbrc.2005.07.028. View

20.

Patolsky F, Gill R, Weizmann Y, Mokari T, Banin U, Willner I . Lighting-up the dynamics of telomerization and DNA replication by CdSe-ZnS quantum dots. J Am Chem Soc. 2003; 125(46):13918-9. DOI: 10.1021/ja035848c. View