Utilizes Siderophores As an Iron Source and FhuDBGC Contributes to Ferrichrome Uptake

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 2023 Nov 16

PMID 37971230

Authors

Jessica L Hastie

Hannah L Carmichael

Bailey M Werner

Kristin E Dunbar

Paul E Carlson Jr

Affiliations

Soon will be listed here.

Abstract

This study is the first example of growing with siderophores as the sole iron source and describes the characterization of the ferric hydroxamate uptake ABC transporter (FhuDBGC). This transporter shows specificity to the siderophore ferrichrome. While not required for pathogenesis, this transporter highlights the redundancy in iron acquisition mechanisms that uses to compete for iron during an infection.

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